Shyra J. Gardai, Ph.D.
Affiliations: | 2002 | University of Colorado Anschutz Medical Campus, Denver, Aurora, CO |
Area:
Immunology, Cell BiologyGoogle:
"Shyra Gardai"Parents
Sign in to add mentor| Peter M. Henson | grad student | 2002 | University of Colorado, Denver | |
| (For whom the bell tolls: An in-depth analysis of the mechanism of granulocyte apoptosis.) | ||||
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Publications
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| Gardai SJ, Mao W, Schüle B, et al. (2013) Elevated alpha-synuclein impairs innate immune cell function and provides a potential peripheral biomarker for Parkinson's disease. Plos One. 8: e71634 |
| Flanagan K, Fitzgerald K, Baker J, et al. (2012) Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS. Plos One. 7: e40443 |
| Janssen WJ, McPhillips KA, Dickinson MG, et al. (2008) Surfactant proteins A and D suppress alveolar macrophage phagocytosis via interaction with SIRP alpha. American Journal of Respiratory and Critical Care Medicine. 178: 158-67 |
| McPhillips K, Janssen WJ, Ghosh M, et al. (2007) TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms. Journal of Immunology (Baltimore, Md. : 1950). 178: 8117-26 |
| Freire-de-Lima CG, Xiao YQ, Gardai SJ, et al. (2006) Apoptotic cells, through transforming growth factor-beta, coordinately induce anti-inflammatory and suppress pro-inflammatory eicosanoid and NO synthesis in murine macrophages. The Journal of Biological Chemistry. 281: 38376-84 |
| Jehle AW, Gardai SJ, Li S, et al. (2006) ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages. The Journal of Cell Biology. 174: 547-56 |
| Gardai SJ, Bratton DL, Ogden CA, et al. (2006) Recognition ligands on apoptotic cells: a perspective. Journal of Leukocyte Biology. 79: 896-903 |
| Gardai SJ, McPhillips KA, Frasch SC, et al. (2005) Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte. Cell. 123: 321-34 |
| Gardai SJ, Whitlock BB, Xiao YQ, et al. (2004) Oxidants inhibit ERK/MAPK and prevent its ability to delay neutrophil apoptosis downstream of mitochondrial changes and at the level of XIAP. The Journal of Biological Chemistry. 279: 44695-703 |
| Gardai SJ, Hildeman DA, Frankel SK, et al. (2004) Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. The Journal of Biological Chemistry. 279: 21085-95 |