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Sangeeta Shrotriya, Ph.D.

Affiliations: 
2013 Pharmaceutical Sciences University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Toxicology, Oncology, Alternative Medicine
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"Sangeeta Shrotriya"
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Rajesh Agarwal grad student 2013 University of Colorado, Denver
 (Anti-cancer and chemopreventive efficacy of grape seed extract against head and neck squamous cell carcinoma through cellular metabolism.)

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Publications

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Somasagara RR, Deep G, Shrotriya S, et al. (2015) Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells. International Journal of Oncology. 46: 1849-57
Shrotriya S, Agarwal R, Sclafani RA. (2015) A perspective on chemoprevention by resveratrol in head and neck squamous cell carcinoma. Advances in Experimental Medicine and Biology. 815: 333-48
Shrotriya S, Tyagi A, Deep G, et al. (2015) Grape seed extract and resveratrol prevent 4-nitroquinoline 1-oxide induced oral tumorigenesis in mice by modulating AMPK activation and associated biological responses. Molecular Carcinogenesis. 54: 291-300
Shrotriya S, Deep G, Lopert P, et al. (2014) Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells. Molecular Carcinogenesis
Derry MM, Raina K, Balaiya V, et al. (2013) Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation. Cancer Prevention Research (Philadelphia, Pa.). 6: 625-33
Shrotriya S, Gagan D, Ramasamy K, et al. (2012) Poly[3-(3, 4-dihydroxyphenyl) glyceric acid] from Comfrey exerts anti-cancer efficacy against human prostate cancer via targeting androgen receptor, cell cycle arrest and apoptosis. Carcinogenesis. 33: 1572-80
Shrotriya S, Deep G, Gu M, et al. (2012) Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells. Carcinogenesis. 33: 848-58
Derry MM, Raina K, Balaiya V, et al. (2012) Abstract A32: Chemopreventive potential of Grape Seed Extract in azoxymethane-induced colon tumorigenesis in the A/J mouse model: interlinking miRNA expression and inflammatory and cytokine signaling Cancer Prevention Research. 5: A32-A32
Shrotriya S, Deep G, Gu M, et al. (2012) Abstract 1598: Grape seed extract induces irreparable DNA damage causing G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells: Potential involvement of reactive oxygen species Cancer Research. 72: 1598-1598
Inturi S, Tewari-Singh N, Gu M, et al. (2011) Mechanisms of sulfur mustard analog 2-chloroethyl ethyl sulfide-induced DNA damage in skin epidermal cells and fibroblasts. Free Radical Biology & Medicine. 51: 2272-80
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