Karla R. Wiehagen, Ph.D.

Affiliations: 
2013 Immunology University of Pennsylvania, Philadelphia, PA, United States 
Area:
Immunology
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"Karla Wiehagen"

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Jonathan Maltzman grad student 2013 Penn
 (Forkhead transcription factors FoxP1 and FoxP4 regulate T cell development and function.)
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Publications

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Travers M, Brown SM, Dunworth M, et al. (2019) DFMO and 5-azacytidine increase M1 macrophages in the tumor microenvironment of murine ovarian cancer. Cancer Research
Stone ML, Chiappinelli KB, Li H, et al. (2017) Epigenetic therapy activates type I interferon signaling in murine ovarian cancer to reduce immunosuppression and tumor burden. Proceedings of the National Academy of Sciences of the United States of America
Verona RI, Wiehagen KR, Girgis NM, et al. (2017) Combination of CD40 agonism and CSF-1R blockade reconditions tumor-associated macrophages and drives potent antitumor immunity. Cancer Immunology Research
Corbo-Rodgers E, Wiehagen KR, Staub ES, et al. (2012) Homeostatic division is not necessary for antigen-specific CD4+ memory T cell persistence. Journal of Immunology (Baltimore, Md. : 1950). 189: 3378-85
Wiehagen KR, Corbo-Rodgers E, Li S, et al. (2012) Foxp4 is dispensable for T cell development, but required for robust recall responses. Plos One. 7: e42273
Wiehagen KR, Corbo E, Schmidt M, et al. (2010) Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells Blood. 116: 5560-5570
Radhakrishnan S, Wiehagen KR, Pulko V, et al. (2010) Induction of a Th1 response from Th2-polarized T cells by activated dendritic cells: Dependence on TCR:Peptide-MHC interaction, ICAM-1, IL-12, and IFN-{gamma} (The Journal of Immunology (2007) 178, (3583-3592)) Journal of Immunology. 184: 6555
Feng X, Ippolito GC, Tian L, et al. (2010) Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development. Blood. 115: 510-8
Radhakrishnan S, Wiehagen KR, Pulko V, et al. (2007) Induction of a Th1 response from Th2-polarized T cells by activated dendritic cells: dependence on TCR:peptide-MHC interaction, ICAM-1, IL-12, and IFN-gamma. Journal of Immunology (Baltimore, Md. : 1950). 178: 3583-92
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