Frédéric Saudou, PhD
Affiliations: | 1999-2013 | Inserm U1005 | Institut Curie, Bures-sur-Yvette, Île-de-France, France |
| 2013- | Grenoble Institute of Neurosciences | Université Grenoble Alpes, INSERM |
Area:
Huntington's disease, intracellular dynamics, axonal transportWebsite:
https://neurosciences.ujf-grenoble.fr/search/team-saudou-intracellular-dynamics-neurodegeneration?language=enGoogle:
"Frédéric Saudou"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| René Hen | grad student | 1989-1993 | Université Strasbourg |
| Jean-Louis Mandel | post-doc | 1994-1996 | Institut de Biologie Moléculaire et Cellulaire (IGBMC) |
| Michael E. Greenberg | post-doc | 1996-1999 | Harvard Medical School - Boston Children's Hospital |
Children
Sign in to add trainee| Jose R. Pineda | post-doc | 2007-2009 | Institut Curie/INSERM, Paris, France (Chemistry Tree) |
BETA: Related publications
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Publications
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| Lenoir S, Lahaye RA, Vitet H, et al. (2022) Pridopidine rescues BDNF/TrkB trafficking dynamics and synapse homeostasis in a Huntington disease brain-on-a-chip model. Neurobiology of Disease. 105857 |
| Virlogeux A, Scaramuzzino C, Lenoir S, et al. (2021) Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice. Science Advances. 7 |
| Agasse F, Mendez-David I, Christaller W, et al. (2020) Chronic Corticosterone Elevation Suppresses Adult Hippocampal Neurogenesis by Hyperphosphorylating Huntingtin. Cell Reports. 32: 107865 |
| Bruyère J, Abada YS, Vitet HM, et al. (2020) Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of Huntingtin. Elife. 9 |
| Asselin L, Rivera Alvarez J, Heide S, et al. (2020) Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity. Nature Communications. 11: 2441 |
| Vitet H, Brandt V, Saudou F. (2020) Traffic signaling: new functions of huntingtin and axonal transport in neurological disease. Current Opinion in Neurobiology. 63: 122-130 |
| Ehinger Y, Bruyère J, Panayotis N, et al. (2020) Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice. Embo Molecular Medicine. e10889 |
| Kacher R, Lamazière A, Heck N, et al. (2019) CYP46A1 gene therapy deciphers the role of brain cholesterol metabolism in Huntington's disease. Brain : a Journal of Neurology |
| Zhang H, Zhang C, Vincent J, et al. (2018) Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington's disease models. Nature Communications. 9: 4272 |
| Galvan L, Francelle L, Gaillard MC, et al. (2018) The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin. Brain : a Journal of Neurology |