TK Kwon

2023- AstraZeneca R&D 
Drug discovery of brain disorders
"TK Kwon"
Mean distance: 13.25 (cluster 11)


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Thaddeus A. Bargiello grad student 2009-2012 Yeshiva University
 (Structural characterization of voltage-gating and ion-permeation mechanisms in connexin hemichannels.)
Solange P. Brown post-doc 2012-2013 Johns Hopkins
Rafael Yuste post-doc 2013-2017 Columbia
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Kwon T, Merchán-Pérez A, Rial Verde EM, et al. (2018) Ultrastructural, Molecular and Functional Mapping of GABAergic Synapses on Dendritic Spines and Shafts of Neocortical Pyramidal Neurons. Cerebral Cortex (New York, N.Y. : 1991)
Cartailler J, Kwon T, Yuste R, et al. (2018) Deconvolution of Voltage Sensor Time Series and Electro-diffusion Modeling Reveal the Role of Spine Geometry in Controlling Synaptic Strength. Neuron
Kwon T, Sakamoto M, Peterka DS, et al. (2017) Attenuation of Synaptic Potentials in Dendritic Spines. Cell Reports. 20: 1100-1110
Bargiello TA, Oh S, Tang Q, et al. (2017) Gating of Connexin Channels by transjunctional-voltage: Conformations and models of open and closed states. Biochimica Et Biophysica Acta
Ha TY, Kim KM, Ko GY, et al. (2015) Variant meso-Rex bypass with transposition of abdominal autogenous vein for the management of idiopathic extrahepatic portal vein obstruction: a retrospective observational study. Bmc Surgery. 15: 116
Kwon T, Dowd TL, Bargiello TA. (2013) The carboxyl terminal residues 220-283 are not required for voltage gating of a chimeric connexin32 hemichannel. Biophysical Journal. 105: 1376-82
Kwon T, Tang Q, Bargiello TA. (2013) Voltage-dependent gating of the Cx32*43E1 hemichannel: conformational changes at the channel entrances. The Journal of General Physiology. 141: 243-59
Abrams CK, Islam M, Mahmoud R, et al. (2013) Functional requirement for a highly conserved charged residue at position 75 in the gap junction protein connexin 32. The Journal of Biological Chemistry. 288: 3609-19
Kwon T, Roux B, Jo S, et al. (2012) Molecular dynamics simulations of the Cx26 hemichannel: insights into voltage-dependent loop-gating. Biophysical Journal. 102: 1341-51
Bargiello TA, Tang Q, Oh S, et al. (2012) Voltage-dependent conformational changes in connexin channels. Biochimica Et Biophysica Acta. 1818: 1807-22
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