Christine Loh
Affiliations: | Pfizer, Inc., San Diego, CA, United States |
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| Ciccone D, Lazari V, Linney I, et al. (2020) 685 A highly selective and potent HPK1 inhibitor enhances immune cell activation and induces robust tumor growth inhibition in a murine syngeneic tumor model Journal For Immunotherapy of Cancer. 8: A724-A724 |
| Ciccone D, Lazari V, Linney I, et al. (2020) A highly selective and potent HPK1 inhibitor enhances immune cell activation and induces robust tumor growth inhibition in a murine syngeneic tumor model European Journal of Cancer. 138: S20 |
| Csibi F, Ji N, Yang B, et al. (2019) Small Molecule-Induced, Selective STAT3 Degradation Leads to Anti-Tumor Activity in STAT3-Dependent Heme Malignancies Blood. 134: 3803-3803 |
| Kelleher JF, Campbell V, Chen J, et al. (2019) Abstract LB-272: KYM-001, a first-in-class oral IRAK4 protein degrader, induces tumor regression in xenograft models of MYD88-mutant ABC DLBCL alone and in combination with BTK inhibition Cancer Research. 79 |
| Csibi F, Ji N, Yang B, et al. (2019) Abstract C054: Discovery of KYM-003, a potent and selective STAT3 degrader with antitumor activity in heme malignancies Molecular Cancer Therapeutics. 18 |
| Henry KL, Kellner D, Bajrami B, et al. (2018) CDK12-mediated transcriptional regulation of noncanonical NF-κB components is essential for signaling. Science Signaling. 11 |
| Yang H, Zhang W, Pan H, et al. (2012) SIRT1 activators suppress inflammatory responses through promotion of p65 deacetylation and inhibition of NF-κB activity. Plos One. 7: e46364 |
| Pau E, Cheung YH, Loh C, et al. (2012) TLR tolerance reduces IFN-alpha production despite plasmacytoid dendritic cell expansion and anti-nuclear antibodies in NZB bicongenic mice. Plos One. 7: e36761 |
| NIWAYAMA S, LOH C, TURK BE, et al. (2010) ChemInform Abstract: Enhanced Potency of Perfluorinated Thalidomide Derivatives for Inhibition of LPS-Induced Tumor Necrosis Factor-α Production is Associated with a Change of Mechanism of Action. Cheminform. 29: no-no |
| Niwayama S, Loh C, Turk BE, et al. (1998) Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-α production is associated with a change of mechanism of action Bioorganic and Medicinal Chemistry Letters. 8: 1071-1076 |