James Nicholas Sleigh

University College London, London, United Kingdom 
neuromuscular disease, motor neuron, sensory neuron, neuromuscular junction, neuropathy, Charcot-Marie-Tooth, spinal muscular atrophy
"James Sleigh"
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Kay Elizabeth Davies grad student 2009-2012 Oxford
David B. Sattelle grad student 2009-2012 Oxford
Kevin Talbot grad student 2009-2012 Oxford
Giampietro Schiavo research scientist 2014- UCL Institute of Neurology, Queen Square
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Sleigh JN, Tosolini AP, Gordon D, et al. (2020) Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes. Cell Reports. 30: 3655-3662.e2
Rossor AM, Sleigh JN, Groves M, et al. (2020) Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy. Acta Neuropathologica Communications. 8: 34
Surana S, Villarroel-Campos D, Lazo OM, et al. (2019) The evolution of the axonal transport toolkit. Traffic (Copenhagen, Denmark)
Williamson MG, Finelli MJ, Sleigh JN, et al. (2019) Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Human Molecular Genetics
Sleigh JN, Rossor AM, Fellows AD, et al. (2019) Axonal transport and neurological disease. Nature Reviews. Neurology
Kalinski AL, Kar AN, Craver J, et al. (2019) Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. The Journal of Cell Biology
Shorrock HK, van der Hoorn D, Boyd PJ, et al. (2018) UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy. Brain : a Journal of Neurology. 141: 2878-2894
Grice SJ, Sleigh JN, Zameel Cader M. (2018) Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in aModel of Peripheral Neuropathy. Frontiers in Molecular Neuroscience. 11: 55
Rossor AM, Reilly MM, Sleigh JN. (2018) Antisense oligonucleotides and other genetic therapies made simple. Practical Neurology
Soliman E, Bianchi F, Sleigh JN, et al. (2018) Aligned electrospun fibers for neural patterning. Biotechnology Letters
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