James Nicholas Sleigh

Affiliations: 
University College London, London, United Kingdom 
Area:
neuromuscular disease, motor neuron, sensory neuron, neuromuscular junction, neuropathy, Charcot-Marie-Tooth, spinal muscular atrophy
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"James Sleigh"
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Publications

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Tosolini AP, Abatecola F, Negro S, et al. (2024) The node of Ranvier influences the axonal transport of mitochondria and signaling endosomes. Iscience. 27: 111158
Surana S, Villarroel-Campos D, Rhymes ER, et al. (2024) The tyrosine phosphatases LAR and PTPRδ act as receptors of the nidogen-tetanus toxin complex. The Embo Journal
Sleigh JN, Mattedi F, Richter S, et al. (2024) Age-specific and compartment-dependent changes in mitochondrial homeostasis and cytoplasmic viscosity in mouse peripheral neurons. Aging Cell. e14250
Rhymes ER, Simkin RL, Qu J, et al. (2024) Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy. Neurobiology of Disease. 106501
Rhymes ER, Simkin RL, Qu J, et al. (2024) Boosting BDNF in muscle rescues impaired axonal transport in a mouse model of DI-CMTC peripheral neuropathy. Biorxiv : the Preprint Server For Biology
Sleigh JN, Villarroel-Campos D, Surana S, et al. (2023) Boosting peripheral BDNF rescues impaired in vivo axonal transport in CMT2D mice. Jci Insight
Lang Q, Schiavo G, Sleigh JN. (2023) imaging of axonal transport in peripheral nerves of rodent forelimbs. Neuronal Signaling. 7: NS20220098
Negro S, Lauria F, Stazi M, et al. (2022) Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor. Acta Neuropathologica Communications. 10: 189
Sleigh JN, Schiavo G. (2022) Neuroscience highlights in 2022: cytoskeletal transport. The Lancet. Neurology. 22: 25-27
Tosolini AP, Sleigh JN, Surana S, et al. (2022) BDNF-dependent modulation of axonal transport is selectively impaired in ALS. Acta Neuropathologica Communications. 10: 121
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