Marco Giovannini, M.D., Ph.D.

Affiliations: 
UCLA School of Medicine, Los Angeles, CA, United States 
Area:
Neurofibromatosis type 2, Schwannomatosis, Meningiomatosis, Rhabdoid Tumors
Website:
https://www.uclahealth.org/head-neck-surgery/marco-giovannini
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"Marco Giovannini"
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Parents

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Glen A. Evans grad student 1991-1993 Salk Institute
Antonius J.M. Berns post-doc 1994-1996 Netherlands Cancer Institute (Chemistry Tree)
Gilles Thomas post-doc 1994-1997 Institut Curie, Paris, France

Children

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Jeremie Vitte research scientist
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Publications

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Roberts DS, Maurya R, Takemon Y, et al. (2019) Linked-read Sequencing Analysis Reveals Tumor-specific Genome Variation Landscapes in Neurofibromatosis Type 2 (NF2) Patients. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 40: e150-e159
Fuse MA, Dinh CT, Vitte J, et al. (2019) Preclinical Assessment of MEK1/2 Inhibitors for Neurofibromatosis Type 2-Associated Schwannomas Reveal Differences in Efficacy and Drug Resistance Development. Neuro-Oncology
Isakson SH, Rizzardi AE, Coutts AW, et al. (2018) Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1. Communications Biology. 1: 158
Paganini I, Capone GL, Vitte J, et al. (2017) Double somatic SMARCB1 and NF2 mutations in sporadic spinal schwannoma. Journal of Neuro-Oncology
Vitte J, Gao F, Coppola G, et al. (2017) Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development. Nature Communications. 8: 300
Shi Y, Bollam SR, White SM, et al. (2016) Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression. Developmental Cell
Bonne NX, Vitte J, Chareyre F, et al. (2016) An allograft mouse model for the study of hearing loss secondary to vestibular schwannoma growth. Journal of Neuro-Oncology
Peyre M, Salaud C, Clermont-Taranchon E, et al. (2015) PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss. Oncotarget. 6: 32713-22
Zoch A, Mayerl S, Schulz A, et al. (2015) Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation. Plos One. 10: e0129151
Klingler E, Martin PM, Garcia M, et al. (2015) The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development (Cambridge, England). 142: 2026-36
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