Max E. Gottesman, M.D., Ph.D.
Affiliations: | Biochemistry and Molecular Biophysics | Columbia University, New York, NY |
Area:
E. coli transcription terminationWebsite:
http://biochemistry.hs.columbia.edu/faculty/gottesman.htmlGoogle:
"Max Gottesman"Bio:
Undergraduate at Swarthmore; M.D. and Ph.D. in pharmacology from Yale.
Parents
Sign in to add mentor| Evangelo S. Canellakis | grad student | Yale | ||
| Fritz Albert Lipmann | post-doc | Rockefeller (Chemistry Tree) | ||
| (Peptide synthesis) | ||||
Children
Sign in to add trainee| Michael D. Ginsberg | grad student | 2002 | Columbia |
| Hyeong C. Kim | grad student | 2004 | Columbia |
| Christal L. Vitiello | grad student | 2012 | Columbia |
| Susan Gottesman | post-doc | NIH |
Collaborators
Sign in to add collaborator| Paul Rösch | collaborator | 2005-2023 | Columbia University Medical School (Microtree) |
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Publications
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| El Sayyed H, Pambos OJ, Stracy M, et al. (2024) Single-molecule tracking reveals the functional allocation, in vivo interactions, and spatial organization of universal transcription factor NusG. Molecular Cell. 84: 926-937.e4 |
| Bailey EJ, Gottesman ME, Gonzalez RL. (2021) NusG-mediated coupling of transcription and translation enhances gene expression by suppressing RNA polymerase backtracking. Journal of Molecular Biology. 167330 |
| Washburn RS, Zuber PK, Sun M, et al. (2020) Escherichia coli NusG Links the Lead Ribosome with the Transcription Elongation Complex. Iscience. 23: 101352 |
| Gottesman ME, Mustaev A. (2019) Change in inorganic phosphate physical state can regulate transcription. Transcription. 1-8 |
| Gottesman ME, Mustaev A. (2019) Ribonucleoside-5'-diphosphates (NDPs) support RNA polymerase transcription, suggesting NDPs may have been substrates for primordial nucleic acid biosynthesis. The Journal of Biological Chemistry |
| Myka KK, Gottesman ME. (2019) DksA and DNA double-strand break repair. Current Genetics |
| Pezone A, Zuchegna C, Tramontano A, et al. (2019) RNA Stabilizes Transcription-Dependent Chromatin Loops Induced By Nuclear Hormones. Scientific Reports. 9: 3925 |
| Myka KK, Küsters K, Washburn R, et al. (2019) DksA-RNA polymerase interactions support new origin formation and DNA repair in Escherichia coli. Molecular Microbiology |
| Zuber PK, Hahn L, Reinl A, et al. (2018) Structure and nucleic acid binding properties of KOW domains 4 and 6-7 of human transcription elongation factor DSIF. Scientific Reports. 8: 11660 |
| Schrank BR, Aparicio T, Li Y, et al. (2018) Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature |