Kevin Wiehe, Ph.D.

Affiliations: 
2008 Boston University, Boston, MA, United States 
Area:
General Biophysics
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"Kevin Wiehe"
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Parents

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Zhiping Weng grad student 2008 Boston University
 (Analysis and prediction of side -chain flexibility in protein -protein recognition.)
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Publications

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McNamara HA, Idris AH, Sutton HJ, et al. (2020) Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response. Cell Host & Microbe
Bradley T, Kuraoka M, Yeh CH, et al. (2020) Immune checkpoint modulation enhances HIV-1 antibody induction. Nature Communications. 11: 948
Easterhoff D, Pollara J, Luo K, et al. (2020) HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions. Jci Insight. 5
Henderson R, Lu M, Zhou Y, et al. (2020) Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements. Nature Communications. 11: 520
Saunders KO, Wiehe K, Tian M, et al. (2019) Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. Science (New York, N.Y.). 366
Easterhoff D, Pollara J, Luo K, et al. (2019) Boosting with AIDSVAX B/E enhances Env constant region 1 and 2 antibody-dependent cellular cytotoxicity breadth and potency. Journal of Virology
Sacks D, Bhiman JN, Wiehe K, et al. (2019) Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage. Plos Pathogens. 15: e1008005
Tay MZ, Wiehe K, Pollara J. (2019) Antibody-Dependent Cellular Phagocytosis in Antiviral Immune Responses. Frontiers in Immunology. 10: 332
Henderson R, Watts BE, Ergin HN, et al. (2019) Selection of immunoglobulin elbow region mutations impacts interdomain conformational flexibility in HIV-1 broadly neutralizing antibodies. Nature Communications. 10: 654
Kisalu NK, Idris AH, Weidle C, et al. (2018) Author Correction: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nature Medicine
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