Robert H. Brown

Affiliations: 
Neurology University of Massachussetts Medical School, Worcester, MA, United States 
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Meijboom KE, Abdallah A, Fordham NP, et al. (2022) CRISPR/Cas9-mediated excision of ALS/FTD-causing hexanucleotide repeat expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro. Nature Communications. 13: 6286
Johnson JO, Chia R, Miller DE, et al. (2021) Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis. Jama Neurology
Peters OM, Weiss A, Metterville J, et al. (2021) Genetic diversity of axon degenerative mechanisms in models of Parkinson's disease. Neurobiology of Disease. 105368
Wainger BJ, Brown RH. (2020) Amyotrophic Lateral Sclerosis: Fuel for the Corticofugal Feud. Annals of Neurology
Mueller C, Berry JD, McKenna-Yasek DM, et al. (2020) Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS. The New England Journal of Medicine. 383: 151-158
Keeler AM, Zieger M, Semple C, et al. (2020) Intralingual and Intrapleural AAV Gene Therapy Prolongs Survival in a SOD1 ALS Mouse Model. Molecular Therapy. Methods & Clinical Development. 17: 246-257
Reichenstein I, Eitan C, Diaz-Garcia S, et al. (2019) Human genetics and neuropathology suggest a link between miR-218 and amyotrophic lateral sclerosis pathophysiology. Science Translational Medicine. 11
Giampetruzzi A, Danielson EW, Gumina V, et al. (2019) Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis. Nature Communications. 10: 3827
Gelfman S, Dugger SA, Araujo Martins Moreno C, et al. (2019) A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS. Genome Research
Borel F, Gernoux G, Sun H, et al. (2018) Safe and effective superoxide dismutase 1 silencing using artificial microRNA in macaques. Science Translational Medicine. 10
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