Adolfo Sequeira, Ph.D.

Affiliations: 
2000-2006 Human Genetics McGill University, Montreal, QC, Canada 
 2007- Psychiatry and Human Behavior University of California Irvine School of Medicine, Irvine, CA, United States 
Area:
Genetics, Major Depressive Disorder, Bipolar Disorder, Schizophrenia, Neuromodulation, Psychiatry, Telomeres
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Publications

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Moyers BA, Loupe JM, Felker SA, et al. (2023) Allele biased transcription factor binding across human brain regions gives mechanistic insight into eQTLs. Biorxiv : the Preprint Server For Biology
Hjelm BE, Ramiro C, Rollins BL, et al. (2022) Large Common Mitochondrial DNA Deletions Are Associated with a Mitochondrial SNP T14798C Near the 3' Breakpoints. Complex Psychiatry. 8: 90-98
Das SC, Hjelm BE, Rollins BL, et al. (2022) Mitochondria DNA copy number, mitochondria DNA total somatic deletions, Complex I activity, synapse number, and synaptic mitochondria number are altered in schizophrenia and bipolar disorder. Translational Psychiatry. 12: 353
Mamdani F, Sequeira A. (2022) Blood-based biomarkers for suicide in depression: moving a step closer to prediction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
Mamdani F, Weber MD, Bunney B, et al. (2022) Identification of potential blood biomarkers associated with suicide in major depressive disorder. Translational Psychiatry. 12: 159
Scaduto P, Sequeira A, Vawter MP, et al. (2020) Preservation of global synaptic excitatory to inhibitory ratio during long postmortem intervals. Scientific Reports. 10: 8626
Limon A, Delbruck E, Yassine A, et al. (2019) Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA receptors. Translational Psychiatry. 9: 218
Hjelm BE, Rollins B, Morgan L, et al. (2019) Splice-Break: exploiting an RNA-seq splice junction algorithm to discover mitochondrial DNA deletion breakpoints and analyses of psychiatric disorders. Nucleic Acids Research
Le-Niculescu H, Roseberry K, Levey DF, et al. (2019) Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs. Molecular Psychiatry
Gonçalves VF, Cappi C, Hagen CM, et al. (2018) A Comprehensive Analysis of Nuclear-Encoded Mitochondrial Genes in Schizophrenia. Biological Psychiatry. 83: 780-789
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