Douglas Cyr, Ph.D.
Affiliations: | Cell Biology | University of North Carolina, Chapel Hill, Chapel Hill, NC |
Area:
Protein Folding, Molecular Chaperones, Mitochondria, Intermediate MetabolismGoogle:
"Douglas Cyr"Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| George Tremblay | grad student | UNC Chapel Hill | |
| Walter Neupert | post-doc | 1993-1995 | University of Munich, Germany |
Children
Sign in to add trainee| J. M. Younger | grad student | 2006 | UNC Chapel Hill |
| Peter M. Douglas | grad student | 2009 | UNC Chapel Hill |
| Daniel W. Summers | grad student | 2011 | UNC Chapel Hill |
| Katie J. Wolfe | grad student | 2013 | UNC Chapel Hill |
| Meredith Rosser | post-doc | Penn State |
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Publications
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| Marszalek J, De Los Rios P, Cyr D, et al. (2023) J-domain proteins: From molecular mechanisms to diseases. Cell Stress & Chaperones. 29: 21-33 |
| Sopha P, Meerod T, Chantrathonkul B, et al. (2023) Novel functions of the ER-located Hsp40s DNAJB12 and DNAJB14 on proteins at the outer mitochondrial membrane under stress mediated by CCCP. Molecular and Cellular Biochemistry |
| Kennedy A, Cyr DM. (2022) DNAJB12 and Hsp70 Mediate Triage of Misfolded Membrane Proteins for Proteasomal versus Lysosomal Degradation. Autophagy Reports. 1: 559-562 |
| Cyr DM, Ramos CH. (2022) Specification of Hsp70 Function by Hsp40 Co-chaperones. Sub-Cellular Biochemistry. 101: 127-139 |
| Zhang R, Malinverni D, Cyr DM, et al. (2022) J-domain protein chaperone circuits in proteostasis and disease. Trends in Cell Biology |
| Singh AK, Fan Y, Balut C, et al. (2019) Biological characterization of F508delCFTR protein processing by the CFTR Corrector ABBV-2222/GLPG2222. The Journal of Pharmacology and Experimental Therapeutics |
| Kampinga HH, Andreasson C, Barducci A, et al. (2018) Function, evolution, and structure of J-domain proteins. Cell Stress & Chaperones |
| Vermulst M, Denney AS, Lang MJ, et al. (2015) Corrigendum: Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8738 |
| Vermulst M, Denney AS, Lang MJ, et al. (2015) Transcription errors induce proteotoxic stress and shorten cellular lifespan. Nature Communications. 6: 8065 |
| Cyr DM, Ramos CH. (2015) Specification of Hsp70 function by Type I and Type II Hsp40. Sub-Cellular Biochemistry. 78: 91-102 |