Kelly Chibale

Affiliations: 
1996- University of Cape Town, Cape Town, Western Cape, South Africa 
Area:
Medicinal chemistry
Website:
http://www.kellychibaleresearch.uct.ac.za/
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"Kelly Chibale"
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Publications

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Okombo J, Kumar M, Redhi D, et al. (2023) Pyrido-Dibemequine Metabolites Exhibit Improved Druglike Features, Inhibit Hemozoin Formation in , and Synergize with Clinical Antimalarials. Acs Infectious Diseases. 9: 653-667
Byl JAW, Mueller R, Bax B, et al. (2023) A Series of Spiropyrimidinetriones that Enhances DNA Cleavage Mediated by Gyrase. Acs Infectious Diseases. 9: 706-715
Singh V, Grzegorzewicz AE, Fienberg S, et al. (2022) 1,3-Diarylpyrazolyl-acylsulfonamides Target HadAB/BC Complex in . Acs Infectious Diseases. 8: 2315-2326
Kaur N, Korkor C, Mobin SM, et al. (2022) Fluorene-Chloroquine Hybrids: Synthesis, in vitro Antiplasmodial Activity, and Inhibition of Heme Detoxification Machinery of Plasmodium falciparum. Chemmedchem. e202200414
Berger A, Knak T, Kiffe-Delf AL, et al. (2022) Total Synthesis of the Antimycobacterial Natural Product Chlorflavonin and Analogs via a Late-Stage Ruthenium(II)-Catalyzed -C(sp)-H-Hydroxylation. Pharmaceuticals (Basel, Switzerland). 15
Govender P, Müller R, Singh K, et al. (2022) Spiropyrimidinetrione DNA Gyrase Inhibitors with Potent and Selective Antituberculosis Activity. Journal of Medicinal Chemistry. 65: 6903-6925
Semenya D, Touitou M, Ribeiro CM, et al. (2021) Structural Rigidification of -Aryl-pyrroles into Indoles Active against Intracellular and Drug-Resistant Mycobacteria. Acs Medicinal Chemistry Letters. 13: 63-69
Khonde LP, Müller R, Boyle GA, et al. (2021) 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in . Journal of Medicinal Chemistry
Mambwe D, Kumar M, Ferger R, et al. (2021) Structure-Activity Relationship Studies Reveal New Astemizole Analogues Active against In Vitro. Acs Medicinal Chemistry Letters. 12: 1333-1341
Navidpour L, Chibale K, Esmaeili S, et al. (2021) Antimalarial activities of ()-2-(nitroheteroarylmethylene)-3(2)-benzofuranone derivatives: , assessment and β-hematin formation inhibition activity. Antimicrobial Agents and Chemotherapy. AAC0268320
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