Stephen J. Ralph
Affiliations: | School of Medical Sciences | Griffith University |
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Publications
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Ralph S, Mani S, Swargiary G, et al. (2023) Therapeutic Targeting of Mitochondrial Plasticity and Redox Control to Overcome Cancer Chemoresistance. Antioxidants & Redox Signaling |
Mani S, Swargiary G, Ralph SJ. (2021) Targeting the redox imbalance in mitochondria: A novel mode for cancer therapy. Mitochondrion. 62: 50-73 |
Clark AM, Magawa C, Pliego-Zamora A, et al. (2021) Tea tree oil extract causes mitochondrial superoxide production and apoptosis as an anticancer agent, promoting tumor infiltrating neutrophils cytotoxic for breast cancer to induce tumor regression. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 140: 111790 |
Ralph SJ, Nozuhur S, ALHulais RA, et al. (2019) Repurposing drugs as pro-oxidant redox modifiers to eliminate cancer stem cells and improve the treatment of advanced stage cancers. Medicinal Research Reviews |
ALHulais RA, Ralph SJ. (2019) Cancer stem cells, stemness markers and selected drug targeting: metastatic colorectal cancer and cyclooxygenase-2/prostaglandin E2 connection to WNT as a model system Journal of Cancer Metastasis and Treatment. 2019 |
Pritchard R, Rodríguez-Enríquez S, Pacheco-Velázquez SC, et al. (2018) Celecoxib inhibits mitochondrial O consumption, promoting ROS dependent death of murine and human metastatic cancer cells via the apoptotic signalling pathway. Biochemical Pharmacology |
Ralph SJ, Nozuhur S, Moreno-Sánchez R, et al. (2018) NSAID celecoxib: a potent mitochondrial pro-oxidant cytotoxic agent sensitizing metastatic cancers and cancer stem cells to chemotherapy Journal of Cancer Metastasis and Treatment. 4: 49 |
Cutler SJ, Doecke JD, Ghazawi I, et al. (2017) Novel STAT binding elements mediate IL-6 regulation of MMP-1 and MMP-3. Scientific Reports. 7: 8526 |
Yu X, Scott SA, Pritchard R, et al. (2015) Redox state influence on human galectin-1 function. Biochimie |
Low P, Clark AM, Chou TC, et al. (2015) Immunomodulatory activity of Melaleuca alternifolia concentrate (MAC): inhibition of LPS-induced NF-κB activation and cytokine production in myeloid cell lines. International Immunopharmacology. 26: 257-64 |