Derek Lessing

Yale University, New Haven, CT 
"Derek Lessing"
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Minajigi A, Froberg JE, Wei C, et al. (2015) Chromosomes. A comprehensive Xist interactome reveals cohesin repulsion and an RNA-directed chromosome conformation. Science (New York, N.Y.). 349
Lessing D, Anguera MC, Lee JT. (2013) X chromosome inactivation and epigenetic responses to cellular reprogramming. Annual Review of Genomics and Human Genetics. 14: 85-110
Spencer RJ, del Rosario BC, Pinter SF, et al. (2011) A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation. Genetics. 189: 441-54
Jung J, Xu K, Lessing D, et al. (2009) Preventing Ataxin-3 protein cleavage mitigates degeneration in a Drosophila model of SCA3. Human Molecular Genetics. 18: 4843-52
Lessing D, Bonini NM. (2009) Maintaining the brain: insight into human neurodegeneration from Drosophila melanogaster mutants. Nature Reviews. Genetics. 10: 359-70
Lessing D, Bonini NM. (2008) Polyglutamine genes interact to modulate the severity and progression of neurodegeneration in Drosophila. Plos Biology. 6: e29
Goldman AL, Van der Goes van Naters W, Lessing D, et al. (2005) Coexpression of two functional odor receptors in one neuron. Neuron. 45: 661-6
Lessing D, Carlson JR. (1999) Chemosensory behavior: The path from stimulus to response Current Opinion in Neurobiology. 9: 766-771
Clyne PJ, Warr CG, Freeman MR, et al. (1999) A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila. Neuron. 22: 327-38
Von Ohlen T, Lessing D, Nusse R, et al. (1997) Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein Proceedings of the National Academy of Sciences of the United States of America. 94: 2404-2409
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