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Mathes F, Gilbert N, Newcomer M. (2022) Non-Competitive Inhibition by a Substrate Mimetic of Human 5-Lipoxygenase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology |
Gilbert NC, Gerstmeier J, Schexnaydre EE, et al. (2020) Structural and mechanistic insights into 5-lipoxygenase inhibition by natural products. Nature Chemical Biology |
Newcomer ME. (2019) Chloride to the rescue. The Journal of Biological Chemistry. 294: 11402-11403 |
Pakhomova S, Boeglin WE, Neau DB, et al. (2019) An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere. Protein Science : a Publication of the Protein Society |
Schexnaydre EE, Gerstmeier J, Garscha U, et al. (2018) A 5‑lipoxygenase-specific sequence motif impedes enzyme activity and confers dependence on a partner protein. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids |
Gilbert NC, Neau DB, Newcomer ME. (2018) Expression of an 8R-Lipoxygenase From the Coral Plexaura homomalla. Methods in Enzymology. 605: 33-49 |
Kodani SD, Bhakta S, Hwang SH, et al. (2018) Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase. Bioorganic & Medicinal Chemistry Letters |
Wang C, Pakhomova S, Newcomer ME, et al. (2017) Structural basis of antifreeze activity of a bacterial multi-domain antifreeze protein. Plos One. 12: e0187169 |
Mashhadi Z, Newcomer ME, Brash AR. (2016) The Thr-His Connection on the Distal Heme of Catalase-Related Hemoproteins: A Hallmark of Reaction with Fatty Acid Hydroperoxides. Chembiochem : a European Journal of Chemical Biology |
Bender G, Schexnaydre EE, Murphy RC, et al. (2016) Membrane-dependent Activities of Human 15-LOX-2 and its Murine Counterpart: Implications for Murine Models of Atherosclerosis. The Journal of Biological Chemistry |