Jessica L Hoffman

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Alcohol, neuroscience, behavioral neuroscience, developmental addiction
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Publications

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Faccidomo S, Saunders BL, May AM, et al. (2024) Ethanol self-administration targets GluA2-containing AMPA receptor expression and synaptic activity in the nucleus accumbens in a manner that drives the positive reinforcing properties of the drug. Psychopharmacology
Faccidomo S, Saunders BL, May AM, et al. (2024) Operant alcohol self-administration targets GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens in a manner that drives the reinforcing properties of the drug. Biorxiv : the Preprint Server For Biology
Effinger DP, Hoffman JL, Mott SE, et al. (2024) Increased reactivity of the paraventricular nucleus of the hypothalamus and decreased threat responding in male rats following psilocin administration. Nature Communications. 15: 5321
Hoffman JL, Faccidomo SP, Taylor SM, et al. (2023) Negative modulation of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner in male mice. Psychopharmacology
Hoffman JL, Faccidomo S, Saunders BL, et al. (2021) Inhibition of AMPA receptors containing TARP γ-8 with JNJ-55511118 shows preclinical efficacy for pharmacotherapeutic treatment of chronic repetitive alcohol self-administration. Alcoholism, Clinical and Experimental Research
Faccidomo S, Cogan ES, Hon OJ, et al. (2021) Calcium-permeable AMPA receptor activity and GluA1 trafficking in the basolateral amygdala regulate operant alcohol self-administration. Addiction Biology. e13049
Hoffman J, Yu J, Kirstein C, et al. (2020) Combined Effects of Repetitive Mild Traumatic Brain Injury and Alcohol Drinking on the Neuroinflammatory Cytokine Response and Cognitive Behavioral Outcomes. Brain Sciences. 10
Hoffman JL, Faccidomo S, Kim M, et al. (2019) Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer's disease. International Review of Neurobiology. 148: 169-230
Stevenson RA, Hoffman JL, Maldonado-Devincci AM, et al. (2019) MGluR5 activity is required for the induction of ethanol behavioral sensitization and associated changes in ERK MAP kinase phosphorylation in the nucleus accumbens shell and lateral habenula. Behavioural Brain Research
Taylor GT, Manzella FM, Huffman J, et al. (2017) Cognition in female rats after blocking conversion of androgens to estrogens. Hormones and Behavior
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