Chenglai Fu
Affiliations: | Tianjin Medical University, China |
Area:
Circulatory systemGoogle:
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Publications
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Qi J, Shi L, Zhu L, et al. (2023) Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsP and InsP in mammalian cells. Journal of Cardiovascular Translational Research |
Qi J, Cheng W, Gao Z, et al. (2023) Itraconazole inhibits endothelial cell migration by disrupting inositol pyrophosphate-dependent focal adhesion dynamics and cytoskeletal remodeling. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 161: 114449 |
Chin AC, Gao Z, Riley AM, et al. (2020) The inositol pyrophosphate 5-InsP drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α. Science Advances. 6 |
Rao F, Cha J, Xu J, et al. (2020) Inositol Pyrophosphates Mediate the DNA-PK/ATM-p53 Cell Death Pathway by Regulating CK2 Phosphorylation of Tti1/Tel2. Molecular Cell. 79: 702 |
Guha P, Tyagi R, Chowdhury S, et al. (2019) IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration. Cell Reports. 26: 2692-2703.e7 |
Rojas T, Cheng W, Gao Z, et al. (2019) Inositol hexakisphosphate kinase 3 promotes focal adhesion turnover via interactions with dynein intermediate chain 2. Proceedings of the National Academy of Sciences of the United States of America |
Nagpal L, Fu C, Snyder SH. (2018) Inositol hexakisphosphate kinase-2 in cerebellar granule cells regulates Purkinje-cells and motor coordination via protein 4.1N. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Fu C, Rojas T, Chin AC, et al. (2018) Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1. Scientific Reports. 8: 7039 |
Fu C, Tyagi R, Chin AC, et al. (2017) Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation. Circulation Research |
Fu C, Xu J, Cheng W, et al. (2017) Neuronal migration is mediated by inositol hexakisphosphate kinase 1 via α-actinin and focal adhesion kinase. Proceedings of the National Academy of Sciences of the United States of America |