Kostyantyn D. Bobyk, Ph.D.

Affiliations: 
2010 Department of Chemistry and Biochemistry University of Oklahoma, Norman, OK, United States 
Area:
Biochemistry
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Parents

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Paul Fabyan Cook grad student 2010 University of Oklahoma
 (Mechanistic and structural studies of saccharopine dehydrogenase from Saccharomyces cerevisiae.)
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Publications

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Bobyk KD, Ballou DP, Rokita SE. (2015) Rapid kinetics of dehalogenation promoted by iodotyrosine deiodinase from human thyroid. Biochemistry. 54: 4487-94
Kumar VP, Thomas LM, Bobyk KD, et al. (2012) Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry. 51: 857-66
Karsten WE, Reyes ZL, Bobyk KD, et al. (2011) Mechanism of the aromatic aminotransferase encoded by the Aro8 gene from Saccharomyces cerevisiae. Archives of Biochemistry and Biophysics. 516: 67-74
Bobyk KD, Kim SG, Kumar VP, et al. (2011) The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH. Archives of Biochemistry and Biophysics. 513: 71-80
Ekanayake DK, Andi B, Bobyk KD, et al. (2010) Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts. The Journal of Biological Chemistry. 285: 20756-68
Mikolosko J, Bobyk K, Zgurskaya HI, et al. (2006) Conformational flexibility in the multidrug efflux system protein AcrA. Structure (London, England : 1993). 14: 577-87
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