Neekesh Dharia

Affiliations: 
Cell Biology Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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"Neekesh Dharia"
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Elizabeth Ann Winzeler grad student 2009 Scripps Institute
 (Plasmodium evolution and drug resistance in vitro and in populations using whole genome technologies.)
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Publications

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Seong BKA, Lin S, Donovan K, et al. (2020) Abstract B50: Targeting EWS/FLI fusion oncoprotein stability/degradation in Ewing sarcoma Cancer Research. 80
Guenther LM, Dharia NV, Ross L, et al. (2018) A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Istvan ES, Mallari JP, Corey VC, et al. (2017) Esterase mutation is a mechanism of resistance to antimalarial compounds. Nature Communications. 8: 14240
Bopp SE, Manary MJ, Bright AT, et al. (2013) Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families. Plos Genetics. 9: e1003293
Meister S, Plouffe DM, Kuhen KL, et al. (2011) Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science (New York, N.Y.). 334: 1372-7
Nam TG, McNamara CW, Bopp S, et al. (2011) A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor. Acs Chemical Biology. 6: 1214-22
Eastman RT, Dharia NV, Winzeler EA, et al. (2011) Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites. Antimicrobial Agents and Chemotherapy. 55: 3908-16
Istvan ES, Dharia NV, Bopp SE, et al. (2011) Validation of isoleucine utilization targets in Plasmodium falciparum. Proceedings of the National Academy of Sciences of the United States of America. 108: 1627-32
Dharia NV, Bright AT, Westenberger SJ, et al. (2010) Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes. Proceedings of the National Academy of Sciences of the United States of America. 107: 20045-50
Dharia NV, Plouffe D, Bopp SE, et al. (2010) Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites. Genome Research. 20: 1534-44
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