Kathryn D. Luderman

Affiliations: 
2014- National Institutes of Health, Bethesda, MD 
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Sibley DR, Luderman KD, Free RB, et al. (2021) Novel Cryo-EM structures of the D1 dopamine receptor unlock its therapeutic potential. Signal Transduction and Targeted Therapy. 6: 205
Luderman KD, Jain P, Benjamin Free R, et al. (2020) Development of Pyrimidone D1 Dopamine Receptor Positive Allosteric Modulators. Bioorganic & Medicinal Chemistry Letters. 127696
Bocarsly ME, da Silva E Silva D, Kolb V, et al. (2019) A Mechanism Linking Two Known Vulnerability Factors for Alcohol Abuse: Heightened Alcohol Stimulation and Low Striatal Dopamine D2 Receptors. Cell Reports. 29: 1147-1163.e5
Luderman KD, Conroy JL, Free RB, et al. (2018) Identification of positive allosteric modulators of the D1 dopamine receptor that act at diverse binding sites. Molecular Pharmacology
Luderman KD, Conroy JL, Free RB, et al. (2016) Structurally Diverse Positive Allosteric Modulators of the D1 Dopamine Receptor Potentiate G‐Protein and β‐Arrestin‐Mediated Signaling The Faseb Journal. 30
Luderman KD, Chen R, Ferris MJ, et al. (2015) Protein kinase C beta regulates the D₂-like dopamine autoreceptor. Neuropharmacology. 89: 335-41
Luderman K, Chen R, Alberts P, et al. (2013) Protein Kinase C β and the Dopamine Transporter Influence Surface D2-Like Dopamine Receptor Localization Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 108
Perry ML, Leinninger GM, Chen R, et al. (2010) Leptin promotes dopamine transporter and tyrosine hydroxylase activity in the nucleus accumbens of Sprague-Dawley rats. Journal of Neurochemistry. 114: 666-74
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