Amit U Joshi

Stanford University, Palo Alto, CA 
Mitochondria, Neurodegeneration, Cardiac dysfunction
"Amit Joshi"
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Chen CH, Ferreira JCB, Joshi AU, et al. (2020) Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes' toxicity. Ebiomedicine. 55: 102753
Haileselassie B, Joshi AU, Minhas PS, et al. (2020) Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy. Journal of Neuroinflammation. 17: 36
Joshi AU, Van Wassenhove LD, Logas KR, et al. (2019) Aldehyde dehydrogenase 2 activity and aldehydic load contribute to neuroinflammation and Alzheimer's disease related pathology. Acta Neuropathologica Communications. 7: 190
Joshi AU, Minhas PS, Liddelow SA, et al. (2019) Fragmented mitochondria released from microglia trigger A1 astrocytic response and propagate inflammatory neurodegeneration. Nature Neuroscience. 22: 1635-1648
Haileselassie B, Mukherjee R, Joshi AU, et al. (2019) Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy. Journal of Molecular and Cellular Cardiology
Joshi AU, Ebert AE, Haileselassie B, et al. (2018) Drp1/Fis1-mediated mitochondrial fragmentation leads to lysosomal dysfunction in cardiac models of Huntington's disease. Journal of Molecular and Cellular Cardiology. 127: 125-133
Minhas PS, Liu L, Moon PK, et al. (2018) Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nature Immunology
Joshi AU, Mochly-Rosen D. (2018) Mortal engines: Mitochondrial bioenergetics and dysfunction in neurodegenerative diseases. Pharmacological Research
Joshi AU, Saw NL, Shamloo M, et al. (2018) Drp1/Fis1 interaction mediates mitochondrial dysfunction, bioenergetic failure and cognitive decline in Alzheimer's disease. Oncotarget. 9: 6128-6143
Joshi AU, Saw NL, Vogel H, et al. (2018) Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis. Embo Molecular Medicine
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