O. Giles Best

Affiliations: 
Faculty of Medicine and Health University of Sydney, Camperdown, New South Wales, Australia 
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Publications

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Shen Y, Crassini K, Sandhu S, et al. (2019) Dual inhibition of MEK1/2 and AKT by binimetinib and MK2206 induces apoptosis of chronic lymphocytic leukemia cells under conditions that mimic the tumor microenvironment. Leukemia & Lymphoma. 1-12
Crassini K, Shen Y, O'Dwyer M, et al. (2018) The dual inhibitor of the phosphoinositol-3 and PIM kinases, IBL-202, is effective against chronic lymphocytic leukaemia cells under conditions that mimic the hypoxic tumour microenvironment. British Journal of Haematology
Crassini KR, Best OG, Mulligan SP. (2018) Immune failure, infection and survival in chronic lymphocytic leukemia. Haematologica. 103: e329
Crassini K, Pyke T, Shen Y, et al. (2018) Inhibition of the Raf-1 kinase inhibitory protein (RKIP) by locostatin induces cell death and reduces the CXCR4-mediated migration of chronic lymphocytic leukemia cells. Leukemia & Lymphoma. 1-12
Crassini K, Shen Y, Stevenson WS, et al. (2018) MEK1/2 inhibition by binimetinib is effective as a single agent and potentiates the actions of Venetoclax and ABT-737 under conditions that mimic the chronic lymphocytic leukaemia (CLL) tumour microenvironment. British Journal of Haematology
Crassini KR, Zhang E, Balendran S, et al. (2018) Humoral immune failure defined by immunoglobulin class and immunoglobulin G subclass deficiency is associated with shorter treatment-free and overall survival in Chronic Lymphocytic Leukaemia. British Journal of Haematology
Shen Y, Best OG, Mulligan SP, et al. (2017) Ibrutinib and idelalisib block immunophenotypic changes associated with the adhesion and activation of CLL cells in the tumor microenvironment. Leukemia & Lymphoma. 1-11
Belov L, Hallal S, Matic K, et al. (2017) Surface Profiling of Extracellular Vesicles from Plasma or Ascites Fluid Using DotScan Antibody Microarrays. Methods in Molecular Biology (Clifton, N.J.). 1619: 263-301
Li J, Best OG, Mulligan SP, et al. (2016) Serum from a subset of patients with chronic lymphocytic leukemia and large local reactions to mosquito bites induces upregulation of CD63 surface expression on basophils in atopic donors. Leukemia & Lymphoma. 1-4
Belov L, Matic KJ, Hallal S, et al. (2016) Extensive surface protein profiles of extracellular vesicles from cancer cells may provide diagnostic signatures from blood samples. Journal of Extracellular Vesicles. 5: 25355
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