John Rossi

Affiliations: 
Psychology Florida Gulf Coast University, Fort Myers, FL, United States 
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Zhou J, Lazar D, Li H, et al. (2018) Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1. Theranostics. 8: 1575-1590
Pang KM, Castanotto D, Li H, et al. (2017) Incorporation of aptamers in the terminal loop of shRNAs yields an effective and novel combinatorial targeting strategy. Nucleic Acids Research
Chung J, Scherer LJ, Gu A, et al. (2014) Optimized lentiviral vectors for HIV gene therapy: multiplexed expression of small RNAs and inclusion of MGMT(P140K) drug resistance gene. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 952-63
Chung J, Zhang J, Li H, et al. (2012) Endogenous MCM7 microRNA cluster as a novel platform to multiplex small interfering and nucleolar RNAs for combinational HIV-1 gene therapy. Human Gene Therapy. 23: 1200-8
Zhou J, Rossi JJ. (2011) Aptamer-targeted RNAi for HIV-1 therapy. Methods of Molecular Biology. 721: 355-371
Zhou J, Rossi JJ. (2011) Progress in RNAi-based Antiviral Therapeutics Methods of Molecular Biology. 721: 67-75
DiGiusto DL, Krishnan A, Li L, et al. (2010) RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma. Science Translational Medicine. 2: 36ra43
Morris KV, Rossi JJ. (2006) Lentivirus-mediated RNA interference therapy for human immunodeficiency virus type 1 infection. Human Gene Therapy. 17: 479-86
Robbins MA, Li M, Leung I, et al. (2006) Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro. Nature Biotechnology. 24: 566-71
Amarzguioui M, Rossi JJ, Kim D. (2005) Approaches for chemically synthesized siRNA and vector‐mediated RNAi Febs Letters. 579: 5974-5981
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