Stephen Cochrane
Affiliations: | 2010-2015 | University of Alberta, Edmonton, Alberta, Canada |
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Sign in to add trainee| Ross Ballantine | grad student | 2017-2020 | Queen's University Belfast |
| Samantha Bann | grad student | 2019-2022 | Queen's University Belfast |
| Milandip Karak | post-doc | 2022- | Queen's University Belfast |
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| Karak M, Cloonan CR, Baker BR, et al. (2024) Optimizations of lipid II synthesis: an essential glycolipid precursor in bacterial cell wall synthesis and a validated antibiotic target. Beilstein Journal of Organic Chemistry. 20: 220-227 |
| Buijs NP, Matheson EJ, Cochrane SA, et al. (2023) Targeting membrane-bound bacterial cell wall precursors: a tried and true antibiotic strategy in nature and the clinic. Chemical Communications (Cambridge, England) |
| Ballantine RD, Al Ayed K, Bann SJ, et al. (2023) Linearization of the Brevicidine and Laterocidine Lipopeptides Yields Analogues That Retain Full Antibacterial Activity. Journal of Medicinal Chemistry |
| Ballantine RD, Al Ayed K, Bann SJ, et al. (2022) Synthesis and structure-activity relationship studies of N-terminal analogues of the lipopeptide antibiotics brevicidine and laterocidine. Rsc Medicinal Chemistry. 13: 1640-1643 |
| Al Ayed K, Ballantine RD, Hoekstra M, et al. (2022) Synthetic studies with the brevicidine and laterocidine lipopeptide antibiotics including analogues with enhanced properties and efficacy. Chemical Science. 13: 3563-3570 |
| Kotsogianni I, Wood TM, Alexander FM, et al. (2021) Binding Studies Reveal Phospholipid Specificity and Its Role in the Calcium-Dependent Mechanism of Action of Daptomycin. Acs Infectious Diseases |
| Bann SJ, Ballantine RD, Cochrane SA. (2021) The tridecaptins: non-ribosomal peptides that selectively target Gram-negative bacteria. Rsc Medicinal Chemistry. 12: 538-551 |
| Cochrane RVK, Alexander FM, Boland C, et al. (2020) From plant to probe: semi-synthesis of labelled undecaprenol analogues allows rapid access to probes for antibiotic targets. Chemical Communications (Cambridge, England) |
| Cochrane SA, Lohans CT. (2020) Breaking down the cell wall: Strategies for antibiotic discovery targeting bacterial transpeptidases. European Journal of Medicinal Chemistry. 194: 112262 |
| Bann SJ, Ballantine RD, McCallion CE, et al. (2019) A Chemical-Intervention Strategy to Circumvent Peptide Hydrolysis by D-Stereoselective Peptidases. Journal of Medicinal Chemistry |