Melvin Khee Shing Leow

Affiliations: 
Singapore Institute for Clinical Sciences, Singapore, Singapore 
Area:
Thyroid homeostasis
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"Melvin Leow"
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Müller P, Leow MK, Dietrich JW. (2022) Minor perturbations of thyroid homeostasis and major cardiovascular endpoints-Physiological mechanisms and clinical evidence. Frontiers in Cardiovascular Medicine. 9: 942971
Li E, Yen PM, Dietrich JW, et al. (2020) Profiling retrospective thyroid function data in complete thyroidectomy patients to investigate the HPT axis set point (PREDICT-IT). Journal of Endocrinological Investigation
Goede SL, Latham KR, Leow MK, et al. (2017) High Resolution Free Triiodothyronine-Thyrotropin (FT3-TSH) Responses to a Single Oral Dose of Liothyronine in Humans: Evidence of Distinct Inter-Individual Differences Unraveled Using an Electrical Network Model. Journal of Biological Systems. 25: 119-143
Leow MK. (2016) A Review of the Phenomenon of Hysteresis in the Hypothalamus-Pituitary-Thyroid Axis. Frontiers in Endocrinology. 7: 64
Leow MK, Goede SL. (2014) The homeostatic set point of the hypothalamus-pituitary-thyroid axis--maximum curvature theory for personalized euthyroid targets. Theoretical Biology & Medical Modelling. 11: 35
Goede SL, Leow MK, Smit JW, et al. (2014) Hypothalamus-pituitary-thyroid feedback control: implications of mathematical modeling and consequences for thyrotropin (TSH) and free thyroxine (FT4) reference ranges. Bulletin of Mathematical Biology. 76: 1270-87
Goede SL, Leow MK, Smit JW, et al. (2014) A novel minimal mathematical model of the hypothalamus-pituitary-thyroid axis validated for individualized clinical applications. Mathematical Biosciences. 249: 1-7
Dietrich JW, Leow MK, Goede SL, et al. (2013) Do thyroid-stimulating hormone, body weight, or body mass index serve as adequate markers to guide levothyroxine dose titration? Journal of the American College of Surgeons. 217: 752-3
Leow MK. (2010) Decline of thyroid hormones following preoperative therapeutic plasma exchange for stabilization of thyrotoxicosis. Journal of Clinical Apheresis. 25: 362-3
Dalan R, Leow MK, Ng DC. (2008) High iodine (substrate) turnover Graves' disease: the intriguing 'rapid responder' variant of thyrotoxicosis. Annals of Clinical Biochemistry. 45: 612-5
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