Jeffrey B. Carroll

Affiliations: 
2004-2010 University of British Columbia, Vancouver, Vancouver, BC, Canada 
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Publications

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Coffey SR, Bragg RM, Minnig S, et al. (2017) Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease. Plos One. 12: e0175968
Carroll JB, Bates GP, Steffan J, et al. (2015) Treating the whole body in Huntington's disease. The Lancet. Neurology. 14: 1135-42
Carroll JB, Deik A, Fossale E, et al. (2015) HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation. Plos One. 10: e0134465
Skotte NH, Southwell AL, Østergaard ME, et al. (2014) Allele-specific suppression of mutant huntingtin using antisense oligonucleotides: providing a therapeutic option for all Huntington disease patients. Plos One. 9: e107434
Southwell AL, Skotte NH, Kordasiewicz HB, et al. (2014) In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 2093-106
Southwell AL, Warby SC, Carroll JB, et al. (2013) A fully humanized transgenic mouse model of Huntington disease. Human Molecular Genetics. 22: 18-34
Wild EJ, Carroll JB. (2012) HDBuzz: empowering patients through accessible education. Trends in Molecular Medicine. 18: 1-3
Carroll JB, Warby SC, Southwell AL, et al. (2011) Potent and selective antisense oligonucleotides targeting single-nucleotide polymorphisms in the Huntington disease gene / allele-specific silencing of mutant huntingtin. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 2178-85
Carroll JB, Southwell AL, Graham RK, et al. (2011) Mice lacking caspase-2 are protected from behavioral changes, but not pathology, in the YAC128 model of Huntington disease. Molecular Neurodegeneration. 6: 59
Huang K, Sanders SS, Kang R, et al. (2011) Wild-type HTT modulates the enzymatic activity of the neuronal palmitoyl transferase HIP14. Human Molecular Genetics. 20: 3356-65
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