Francis Shue
Affiliations: | Mayo Clinic Graduate School of Biomedical Sciences |
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Parents
Sign in to add mentor| Michael R. Drew | research assistant | 2012-2018 | Center for Learning and Memory, UT Austin |
| Guojun Bu | grad student | 2019- | Mayo Clinic Florida (Cell Biology Tree) |
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Publications
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| Liu CC, Wang N, Chen Y, et al. (2023) Cell-autonomous effects of APOE4 in restricting microglial response in brain homeostasis and Alzheimer's disease. Nature Immunology |
| Macyczko JR, Wang N, Lu W, et al. (2023) Upregulation of sFRP1 Is More Profound in Female than Male 5xFAD Mice and Positively Associated with Amyloid Pathology. Journal of Alzheimer's Disease : Jad |
| Inoue Y, Shue F, Bu G, et al. (2023) Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer's disease. Molecular Neurodegeneration. 18: 46 |
| Qiao W, Chen Y, Zhong J, et al. (2023) Correction: Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology. Molecular Neurodegeneration. 18: 28 |
| Oue H, Yamazaki Y, Qiao W, et al. (2023) LRP1 in vascular mural cells modulates cerebrovascular integrity and function in the presence of APOE4. Jci Insight. 8 |
| Qiao W, Chen Y, Zhong J, et al. (2023) Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology. Molecular Neurodegeneration. 18: 8 |
| Wang N, Wang M, Jeevaratnam S, et al. (2022) Opposing effects of apoE2 and apoE4 on microglial activation and lipid metabolism in response to demyelination. Molecular Neurodegeneration. 17: 75 |
| Liu CC, Zhao J, Fu Y, et al. (2022) Peripheral apoE4 enhances Alzheimer's pathology and impairs cognition by compromising cerebrovascular function. Nature Neuroscience. 25: 1020-1033 |
| Zhao J, Lu W, Ren Y, et al. (2021) Correction to: Apolipoprotein E regulates lipid metabolism and α‑synuclein pathology in human iPSC‑derived cerebral organoids. Acta Neuropathologica |
| Liu CC, Murray ME, Li X, et al. (2021) -Jacksonville (V236E) variant reduces self-aggregation and risk of dementia. Science Translational Medicine. 13: eabc9375 |