Madeleine Héroux
Affiliations: | Biochemistry and Molecular Medicine | Université de Montréal, Montréal, Canada |
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| Wright SC, Avet C, Gaitonde SA, et al. (2024) Conformation- and activation-based BRET sensors differentially report on GPCR-G protein coupling. Science Signaling. 17: eadi4747 |
| Lupisella J, St-Onge S, Carrier M, et al. (2022) Molecular Mechanisms of Desensitization Underlying the Differential Effects of Formyl Peptide Receptor 2 Agonists on Cardiac Structure-Function Post Myocardial Infarction. Acs Pharmacology & Translational Science. 5: 892-906 |
| Avet C, Mancini A, Breton B, et al. (2022) Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs. Elife. 11 |
| García RA, Lupisella JA, Ito BR, et al. (2021) Selective FPR2 Agonism Promotes a Proresolution Macrophage Phenotype and Improves Cardiac Structure-Function Post Myocardial Infarction. Jacc. Basic to Translational Science. 6: 676-689 |
| Wright SC, Lukasheva V, Le Gouill C, et al. (2021) BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G activation at early endosomes. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Gargalovic P, Wong P, Onorato J, et al. (2021) In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure. Circulation. Heart Failure. CIRCHEARTFAILURE1200 |
| García RA, Ito BR, Lupisella JA, et al. (2019) Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment. Jacc. Basic to Translational Science. 4: 905-920 |
| Katzman BM, Cox BD, Prosser AR, et al. (2019) Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor. Acs Medicinal Chemistry Letters. 10: 67-73 |
| Volpi C, Mondanelli G, Pallotta MT, et al. (2015) Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells. Neuropharmacology |
| Peters MF, Vaillancourt F, Heroux M, et al. (2010) Comparing label-free biosensors for pharmacological screening with cell-based functional assays. Assay and Drug Development Technologies. 8: 219-27 |