Pierre Couvineau

Affiliations: 
Biochemistry and Molecular Medicine Université de Montréal, Montréal, Canada 
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"Pierre Couvineau"
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Ehrlich AT, Couvineau P, Schamiloglu S, et al. (2022) Visualization of real-time receptor endocytosis in dopamine neurons enabled by NTSR1-Venus knock-in mice. Frontiers in Cellular Neuroscience. 16: 1076599
Tran K, Sainsily X, Côté J, et al. (2022) Size-Reduced Macrocyclic Analogues of [Pyr]-apelin-13 Showing Negative Gα Bias Still Produce Prolonged Cardiac Effects. Journal of Medicinal Chemistry. 65: 531-551
Ehrlich AT, Semache M, Couvineau P, et al. (2021) Ackr3-Venus knock-in mouse lights up brain vasculature. Molecular Brain. 14: 151
Budzinski J, Maschauer S, Kobayashi H, et al. (2021) Bivalent ligands promote endosomal trafficking of the dopamine D3 receptor-neurotensin receptor 1 heterodimer. Communications Biology. 4: 1062
Trân K, Van Den Hauwe R, Sainsily X, et al. (2021) Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile. Journal of Medicinal Chemistry
Trân K, Murza A, Sainsily X, et al. (2020) Structure-Activity Relationship and Bioactivity of Short Analogues of ELABELA as Agonists of the Apelin Receptor. Journal of Medicinal Chemistry
Couvineau P, Llorens-Cortes C, Iturrioz X. (2020) Elabela/Toddler and apelin bind differently to the apelin receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 34: 7989-8000
Wang W, Shen M, Fischer C, et al. (2019) Apelin protects against abdominal aortic aneurysm and the therapeutic role of neutral endopeptidase resistant apelin analogs. Proceedings of the National Academy of Sciences of the United States of America
Couvineau P, Ehrlich A, Semache M, et al. (2019) Monitoring Signalling and Trafficking of Neurotensin Type 1 Receptor in Animal Model using Fluorescent‐based Methods The Faseb Journal. 33
Nicole P, Couvineau P, Jamin N, et al. (2015) Crucial role of the orexin-B C-terminus in the induction of OX1 receptor-mediated apoptosis: analysis by alanine scanning, molecular modelling and site-directed mutagenesis. British Journal of Pharmacology. 172: 5211-23
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