Jerome Mertens
Affiliations: | University of Innsbruck, Innsbruck, Tirol, Austria |
Area:
induced neurons, Alzheimer's Disease, aging, neurodegeneration, iPSCs, neural stem cells, reprogrammingGoogle:
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Publications
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| Herdy JR, Mertens J, Gage FH. (2024) Neuronal senescence may drive brain aging. Science (New York, N.Y.). 384: 1404-1406 |
| Li Y, Munoz-Mayorga D, Nie Y, et al. (2024) Microglial lipid droplet accumulation in tauopathy brain is regulated by neuronal AMPK. Cell Metabolism |
| Traxler L, Borgogno O, Mertens J. (2024) Ignorance is bliss: Inhibition of proteomic stress sensing improves direct neuronal conversion. Neuron. 112: 1035-1037 |
| Castillo Bautista CM, Eismann K, Gentzel M, et al. (2023) Obatoclax Rescues FUS-ALS Phenotypes in iPSC-Derived Neurons by Inducing Autophagy. Cells. 12 |
| Traxler L, Lucciola R, Herdy JR, et al. (2023) Neural cell state shifts and fate loss in ageing and age-related diseases. Nature Reviews. Neurology |
| Herdy JR, Traxler L, Agarwal RK, et al. (2022) Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's disease. Cell Stem Cell. 29: 1637-1652.e6 |
| van den Hurk M, Lau S, Marchetto MC, et al. (2022) Druggable transcriptomic pathways revealed in Parkinson's patient-derived midbrain neurons. Npj Parkinson's Disease. 8: 134 |
| Traxler L, Herdy JR, Stefanoni D, et al. (2022) Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metabolism |
| Böhnke L, Zhou-Yang L, Pelucchi S, et al. (2022) Chemical Replacement of Noggin with Dorsomorphin Homolog 1 for Cost-Effective Direct Neuronal Conversion. Cellular Reprogramming |
| Soni A, Klütsch D, Hu X, et al. (2021) Improved Method for Efficient Generation of Functional Neurons from Murine Neural Progenitor Cells. Cells. 10 |