Sylvain Lesné
Affiliations: | University of Minnesota Medical School, Minneapolis, MN, United States |
Area:
Neuroscience, Alzheimer's diseaseGoogle:
"Sylvain Lesné"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Alain Buisson | grad student | 1999-2002 | Université de Caen Basse Normandie |
| Denis Vivien | grad student | 1999-2002 | Université de Caen Basse Normandie |
Children
Sign in to add trainee| Megan Larson | grad student | 2010-2013 | University of Minnesota - Minneapolis |
| Susan Greimel | grad student | 2011-2014 | University of Minnesota Medical School |
| Fatou Amar | grad student | 2010-2015 | University of Minnesota Medical School |
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Publications
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| Brown JL, Hart DW, Boyle GE, et al. (2022) SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex. Acta Neuropathologica Communications. 10: 180 |
| Nguyen PH, Ramamoorthy A, Sahoo BR, et al. (2021) Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis. Chemical Reviews |
| Kayed R, Dettmer U, Lesné SE. (2020) Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk. Journal of Parkinson's Disease |
| Singh B, Covelo A, Martell-Martínez H, et al. (2019) Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy. Acta Neuropathologica |
| Khan SS, LaCroix M, Boyle G, et al. (2018) Bidirectional modulation of Alzheimer phenotype by alpha-synuclein in mice and primary neurons. Acta Neuropathologica |
| Chiang ACA, Fowler SW, Reddy R, et al. (2017) Discrete pools of oligomeric amyloid-β track with spatial learning deficits in a mouse model of Alzheimer amyloidosis. The American Journal of Pathology |
| Larson ME, Greimel SJ, Amar F, et al. (2017) Selective lowering of synapsins induced by oligomeric α-synuclein exacerbates memory deficits. Proceedings of the National Academy of Sciences of the United States of America |
| Amar F, Sherman MA, Rush T, et al. (2017) The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation. Science Signaling. 10 |
| Sherman MA, LaCroix M, Amar F, et al. (2016) Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9647-58 |
| Alfonso SI, Callender JA, Hooli B, et al. (2016) Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease. Science Signaling. 9: ra47 |