Paul James Coffer

Affiliations: 
2005- Biomedical genetics Utrecht University, Utrecht, Netherlands 
Website:
https://profs.library.uu.nl/index.php/profrec/getprofdata/407/1/2/0
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"Paul James Coffer" OR "Paul J Coffer"

Parents

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James R. Woodgett grad student 1991 Council for National Academic Awards (Physics Tree)
 (The identification, cloning and characterisation of novel mammalian protein-serine kinase genes)

Children

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Koen Schepers post-doc 2012-2015 Utrecht (Chemistry Tree)
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Publications

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Lourenço AR, Roukens MG, Seinstra D, et al. (2020) C/EBPɑ is crucial determinant of epithelial maintenance by preventing epithelial-to-mesenchymal transition. Nature Communications. 11: 785
Fleskens V, Minutti CM, Wu X, et al. (2019) Nemo-like Kinase Drives Foxp3 Stability and Is Critical for Maintenance of Immune Tolerance by Regulatory T Cells. Cell Reports. 26: 3600-3612.e6
Vervoort SJ, de Jong OG, Roukens MG, et al. (2018) Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis. Elife. 7
Braccioli L, Vervoort SJ, Puma G, et al. (2018) SOX4 inhibits oligodendrocyte differentiation of embryonic neural stem cells in vitro by inducing Hes5 expression. Stem Cell Research. 33: 110-119
van Loosdregt J, Coffer PJ. (2018) The Role of WNT Signaling in Mature T Cells: T Cell Factor Is Coming Home. Journal of Immunology (Baltimore, Md. : 1950). 201: 2193-2200
Petrelli A, Mijnheer G, Hoytema van Konijnenburg DP, et al. (2018) PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation. The Journal of Clinical Investigation. 128: 4669-4681
Ribeiro D, Melão A, van Boxtel R, et al. (2018) STAT5 is essential for IL-7-mediated viability, growth, and proliferation of T-cell acute lymphoblastic leukemia cells. Blood Advances. 2: 2199-2213
Zaiss DMW, Coffer PJ. (2018) Forkhead box transcription factors as context-dependent regulators of lymphocyte homeostasis. Nature Reviews. Immunology. 18: 703-715
Vervoort SJ, Lourenço AR, Tufegdzic Vidakovic A, et al. (2018) SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis. Nucleic Acids Research. 46: 9578-9590
Mocholi E, Dowling SD, Botbol Y, et al. (2018) Autophagy Is a Tolerance-Avoidance Mechanism that Modulates TCR-Mediated Signaling and Cell Metabolism to Prevent Induction of T Cell Anergy. Cell Reports. 24: 1136-1150
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