Mariliz Ortiz-Maldonado

Affiliations: 
DuPont IB 
Area:
Biochemistry, Formulations, Starch Biochemistry
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"Mariliz Ortiz-Maldonado"
Mean distance: 9.64
 
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David P. Ballou grad student 2000 University of Michigan
 (Insights on the mechanism of Pseudomonas aeruginosa p-hydroxybenzoate hydroxylase from QSAR studies using 8-substituted flavins.)
Vincent Massey grad student 2000 University of Michigan
 (Insights on the mechanism of Pseudomonas aeruginosa p-hydroxybenzoate hydroxylase from QSAR studies using 8-substituted flavins.)
Vincent Massey grad student 2000 University of Michigan
 (Insights on the mechanism of Pseudomonas aeruginosa p-hydroxybenzoate hydroxylase from QSAR studies using 8-substituted flavins.)
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Publications

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Hwang JD, Ortiz-Maldonado M, Paramonov S. (2015) Delivery of Formulated Industrial Enzymes with Acoustic Technology. Journal of Laboratory Automation
Conrad JA, Ortiz-Maldonado M, Hoppe SW, et al. (2014) Detection of intermediates in the oxidative half-reaction of the FAD-dependent thymidylate synthase from Thermotoga maritima: carbon transfer without covalent pyrimidine activation. Biochemistry. 53: 5199-207
Chakraborty S, Ortiz-Maldonado M, Entsch B, et al. (2010) Studies on the mechanism of p-hydroxyphenylacetate 3-hydroxylase from Pseudomonas aeruginosa: A system composed of a small flavin reductase and a large flavin-dependent oxygenase Biochemistry. 49: 372-385
Cole LJ, Entsch B, Ortiz-Maldonado M, et al. (2005) Properties of p-Hydroxybenzoate hydroxylase when stabilized in its Open conformation Biochemistry. 44: 14807-14817
Ortiz-Maldonado M, Entsch B, Ballou DP. (2004) Oxygen reactions in p-Hydroxybenzoate hydroxylase utilize the H-bond network during catalysis Biochemistry. 43: 15246-15257
Ortiz-Maldonado M, Cole LJ, Dumas SM, et al. (2004) Increased Positive Electrostatic Potential in p-Hydroxybenzoate Hydroxylase Accelerates Hydroxylation but Slows Turnover Biochemistry. 43: 1569-1579
Ortiz-Maldonado M, Entsch B, Ballou DP. (2003) Conformational changes combined with charge-transfer interactions are essential for reduction in catalysis by p-Hydroxybenzoate hydroxylase Biochemistry. 42: 11234-11242
Wang J, Ortiz-Maldonado M, Entsch B, et al. (2002) Protein and ligand dynamics in 4-hydroxybenzoate hydroxylase. Proceedings of the National Academy of Sciences of the United States of America. 99: 608-13
Ortiz-Maldonado M, Aeschliman SM, Ballou DP, et al. (2001) Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin. Biochemistry. 40: 8705-16
Ortiz-Maldonado M, Ballou DP, Massey V. (2001) A rate-limiting conformational change of the flavin in p-hydroxybenzoate hydroxylase is necessary for ligand exchange and catalysis: studies with 8-mercapto- and 8-hydroxy-flavins. Biochemistry. 40: 1091-101
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