Jason S Meyer, PhD

Affiliations: 
Medical and Molecular Genetics Indiana University School of Medicine, Indianapolis, IN, United States 
Area:
stem cells, vision research, neurodegeneration, retina
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Parents

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Mark D. Kirk grad student 1999-2004 University of Missouri - Columbia
 (Characterization and therapeutic transplantation of stem cells.)
Su-Chun Zhang post-doc 2005-2007 UW Madison
David Gamm post-doc 2007-2010 UW Madison
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Publications

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Gomes C, Huang KC, Harkin J, et al. (2024) Induction of astrocyte reactivity promotes neurodegeneration in human pluripotent stem cell models. Stem Cell Reports
Harkin J, Peña KH, Gomes C, et al. (2024) A highly reproducible and efficient method for retinal organoid differentiation from human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2317285121
Lavekar SS, Harkin J, Hernandez M, et al. (2023) Development of a three-dimensional organoid model to explore early retinal phenotypes associated with Alzheimer's disease. Scientific Reports. 13: 13827
Huang KC, Gomes C, Meyer JS. (2023) Retinal Ganglion Cells in a Dish: Current Strategies and Recommended Best Practices for Effective In Vitro Modeling of Development and Disease. Handbook of Experimental Pharmacology
Surma M, Anbarasu K, Dutta S, et al. (2023) Enhanced mitochondrial biogenesis promotes neuroprotection in human pluripotent stem cell derived retinal ganglion cells. Communications Biology. 6: 218
Huang KC, Gomes C, Shiga Y, et al. (2023) Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma. Biorxiv : the Preprint Server For Biology
Gomes C, VanderWall KB, Pan Y, et al. (2022) Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells. Stem Cell Reports
Fligor CM, Lavekar SS, Harkin J, et al. (2021) Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids. Stem Cell Reports
VanderWall KB, Lu B, Alfaro JS, et al. (2020) Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease. Scientific Reports. 10: 17359
Fligor CM, Huang KC, Lavekar SS, et al. (2020) Differentiation of retinal organoids from human pluripotent stem cells. Methods in Cell Biology. 159: 279-302
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