Sebastián Abarzúa

Affiliations: 
Universidad Andrés Bello, Santiago, Región Metropolitana, Chile 
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"Sebastián Abarzúa"
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Publications

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Rojas F, Aguilar R, Almeida S, et al. (2023) Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43 mutation display a mild reactive state and release polyP toxic to motoneurons. Frontiers in Cell and Developmental Biology. 11: 1226604
Arredondo C, Cefaliello C, Dyrda A, et al. (2022) Excessive release of inorganic phosphate by ALS/FTD astrocytes causes non-cell-autonomous toxicity to motoneurons. Neuron
Jury N, Abarzua S, Diaz I, et al. (2020) Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice. Clinical Epigenetics. 12: 32
Rojas F, Gonzalez D, Cortes N, et al. (2015) Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Frontiers in Cellular Neuroscience. 9: 203
Rojas F, Cortes N, Abarzua S, et al. (2014) Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress. Frontiers in Cellular Neuroscience. 8: 24
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