Jules Hancox

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 
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"Jules Hancox"
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Hancox JC, Copeland CS, Harmer SC, et al. (2023) New synthetic cannabinoids and the potential for cardiac arrhythmia risk. Journal of Molecular and Cellular Cardiology Plus. 6: 100049
Helliwell MV, Zhang Y, El Harchi A, et al. (2023) Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue. Pharmaceuticals (Basel, Switzerland). 16
El Harchi A, Hancox JC. (2023) hERG agonists pose challenges to web-based machine learning methods for prediction of drug-hERG channel interaction. Journal of Pharmacological and Toxicological Methods. 123: 107293
Butler AS, Hancox JC, Marrion NV. (2022) Preferential formation of human heteromeric SK2:SK3 channels limits homomeric SK channel assembly and function. The Journal of Biological Chemistry. 299: 102783
Zhang Y, Grimwood AL, Hancox JC, et al. (2022) Evolutionary coupling analysis guides identification of mistrafficking-sensitive variants in cardiac K channels: Validation with hERG. Frontiers in Pharmacology. 13: 1010119
Al-Moubarak E, Shiels HA, Zhang Y, et al. (2021) Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant. Cellular and Molecular Life Sciences : Cmls
Al-Moubarak E, Sharifi M, Hancox JC. (2021) Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel-A Drug Antitarget. Frontiers in Cardiovascular Medicine. 8: 645172
Zhang Y, Dempsey CE, Hancox JC. (2020) Electrophysiological characterization of the modified hERG potassium channel used to obtain the first cryo-EM hERG structure. Physiological Reports. 8: e14568
Caves RE, Carpenter A, Choisy SC, et al. (2020) Inhibition of voltage-gated Na currents by eleclazine in rat atrial and ventricular myocytes. Heart Rhythm O2. 1: 206-214
Carpenter A, Chambers OJ, El Harchi A, et al. (2020) COVID-19 Management and Arrhythmia: Risks and Challenges for Clinicians Treating Patients Affected by SARS-CoV-2. Frontiers in Cardiovascular Medicine. 7: 85
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