Keith T Akama

Affiliations: 
NGM Biopharmaceuticals 
Area:
Biologics
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"Keith Akama"
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Publications

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Waters EM, Thompson LI, Patel P, et al. (2015) G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2384-97
Akama KT, Thompson LI, Milner TA, et al. (2013) Post-synaptic density-95 (PSD-95) binding capacity of G-protein-coupled receptor 30 (GPR30), an estrogen receptor that can be identified in hippocampal dendritic spines. The Journal of Biological Chemistry. 288: 6438-50
McEwen BS, Akama KT, Spencer-Segal JL, et al. (2012) Estrogen effects on the brain: actions beyond the hypothalamus via novel mechanisms. Behavioral Neuroscience. 126: 4-16
Williams TJ, Akama KT, Knudsen MG, et al. (2011) Ovarian hormones influence corticotropin releasing factor receptor colocalization with delta opioid receptors in CA1 pyramidal cell dendrites. Experimental Neurology. 230: 186-96
Yildirim M, Janssen WG, Lou WY, et al. (2011) Effects of estrogen and aging on the synaptic distribution of phosphorylated Akt-immunoreactivity in the CA1 region of the female rat hippocampus. Brain Research. 1379: 98-108
Yuen GS, McEwen BS, Akama KT. (2011) LIM kinase mediates estrogen action on the actin depolymerization factor Cofilin. Brain Research. 1379: 44-52
Aher CV, Duwaerts CC, Akama KT, et al. (2010) Effects of acute diuresis stress on egr-1 (zif268) mRNA levels in brain regions associated with motivated behavior. Brain Research Bulletin. 81: 114-9
Nakamura NH, Akama KT, Yuen GS, et al. (2007) Thinking outside the pyramidal cell: unexplored contributions of interneurons and neuropeptide Y to estrogen-induced synapse formation in the hippocampus. Reviews in the Neurosciences. 18: 1-13
Akama KT, McEwen BS. (2005) Gene therapy to bet on: protecting neurons from stress hormones. Trends in Pharmacological Sciences. 26: 169-72
Nakamura NH, Rosell DR, Akama KT, et al. (2004) Estrogen and ovariectomy regulate mRNA and protein of glutamic acid decarboxylases and cation-chloride cotransporters in the adult rat hippocampus. Neuroendocrinology. 80: 308-23
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