Karen J. Tonsfeldt, Ph.D.

Affiliations: 
Reproductive Medicine University of California, San Diego, La Jolla, CA 
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"Karen Tonsfeldt"
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Parents

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Patrick E. Chappell research assistant 2007-2009 Oregon State
Susan L. Ingram grad student 2009-2014 OHSU
Pamela Mellon post-doc 2015- UCSD School of Medicine
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Publications

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Van Loh BM, Yaw AM, Breuer JA, et al. (2023) The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice. Frontiers in Endocrinology. 14: 1269672
Cassin J, Stamou MI, Keefe KW, et al. (2023) Heterozygous mutations in SOX2 may cause idiopathic hypogonadotropic hypogonadism via dominant-negative mechanisms. Jci Insight
Tonsfeldt KJ, Cui LJ, Lee J, et al. (2022) Female fertility does not require in suprachiasmatic nucleus neurons expressing arginine vasopressin, vasoactive intestinal peptide, or neuromedin-S. Frontiers in Endocrinology. 13: 956169
Lavalle SN, Chou T, Hernandez J, et al. (2022) Deletion of the homeodomain gene Six3 from kisspeptin neurons causes subfertility in female mice. Molecular and Cellular Endocrinology. 546: 111577
Tonsfeldt KJ, Mellon PL, Hoffmann HM. (2021) Circadian Rhythms in the Neuronal Network Timing the Luteinizing Hormone Surge. Endocrinology
Ho EV, Shi C, Cassin J, et al. (2021) Reproductive Deficits Induced by Prenatal Anti-Mullerian Hormone Exposure Require Androgen Receptor in Kisspeptin Cells. Endocrinology
Hoffmann HM, Meadows JD, Breuer JA, et al. (2021) The transcription factors SIX3 and VAX1 are required for suprachiasmatic nucleus circadian output and fertility in female mice. Journal of Neuroscience Research
Lavalle SN, Chou T, Hernandez J, et al. (2021) Kiss1 is differentially regulated in male and female mice by the homeodomain transcription factor VAX1. Molecular and Cellular Endocrinology. 111358
Schoeller EL, Tonsfeldt KJ, Sinkovich M, et al. (2021) Growth Hormone Pulses and Liver Gene Expression are Differentially Regulated by the Circadian Clock Gene Bmal1. Endocrinology
Nicholas DA, Knight VS, Tonsfeldt KJ, et al. (2020) GLUT1-mediated glycolysis supports GnRH-induced secretion of luteinizing hormone from female gonadotropes. Scientific Reports. 10: 13063
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