Paolo Giacobini

Affiliations: 
INSERM - France 
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"Paolo Giacobini"
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Paiva I, Seguin J, Grgurina I, et al. (2024) Dysregulated expression of cholesterol biosynthetic genes in Alzheimer's disease alters epigenomic signatures of hippocampal neurons. Neurobiology of Disease. 106538
Cotellessa L, Giacobini P. (2024) Role of Anti-Müllerian Hormone in the Central Regulation of Fertility. Seminars in Reproductive Medicine
Silva MSB, Decoster L, Delpouve G, et al. (2023) Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice. Ebiomedicine. 97: 104850
Sauve F, Nampoothiri S, Clarke SA, et al. (2023) Long-COVID cognitive impairments and reproductive hormone deficits in men may stem from GnRH neuronal death. Ebiomedicine. 96: 104784
Barbotin AL, Mimouni NEH, Kuchcinski G, et al. (2023) Hypothalamic neuroglial plasticity is regulated by anti-Müllerian hormone and disrupted in polycystic ovary syndrome. Ebiomedicine. 90: 104535
Yu Q, Gamayun I, Wartenberg P, et al. (2023) Bitter taste cells in the ventricular walls of the murine brain regulate glucose homeostasis. Nature Communications. 14: 1588
Cotellessa L, Marelli F, Duminuco P, et al. (2023) Defective Jagged1 signaling impacts GnRH development and contributes to congenital hypogonadotropic hypogonadism. Jci Insight
Chachlaki K, Messina A, Delli V, et al. (2022) mutations cause hypogonadotropic hypogonadism with sensory and cognitive deficits that can be reversed in infantile mice. Science Translational Medicine. 14: eabh2369
Wang Y, Madhusudan S, Cotellessa L, et al. (2022) Deciphering the transcriptional landscape of human pluripotent stem cell-derived GnRH neurons: the role of Wnt signaling in patterning the neural fate. Stem Cells (Dayton, Ohio)
Manfredi-Lozano M, Leysen V, Adamo M, et al. (2022) GnRH replacement rescues cognition in Down syndrome. Science (New York, N.Y.). 377: eabq4515
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