Arthur Christopoulos

Affiliations: 
Drug Discovery Biology Faculty of Pharmacy and Pharmaceutical Sciences 
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"Arthur Christopoulos"
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Rahman SN, McNaught-Flores DA, Huppelschoten Y, et al. (2023) Structural and Molecular Determinants for Isoform Bias at Human Histamine H Receptor Isoforms. Acs Chemical Neuroscience
Saito A, Alvi S, Christopoulos A, et al. (2022) Therapeutic potential of allosteric modulators for the treatment of gastrointestinal motility disorders. British Journal of Pharmacology
Jiang Y, Yeasmin M, Gondin AB, et al. (2022) Importance of receptor expression in the classification of novel ligands at the M muscarinic acetylcholine receptor. British Journal of Pharmacology
Piper SJ, Deganutti G, Lu J, et al. (2022) Understanding VPAC receptor family peptide binding and selectivity. Nature Communications. 13: 7013
Dwomoh L, Rossi M, Scarpa M, et al. (2022) M muscarinic receptor activation reduces the molecular pathology and slows the progression of prion-mediated neurodegenerative disease. Science Signaling. 15: eabm3720
Nguyen HTM, van der Westhuizen ET, Langmead CJ, et al. (2022) Opportunities and challenges for the development of M1 muscarinic receptor positive allosteric modulators in the treatment for neurocognitive deficits. British Journal of Pharmacology
Deo O, Alvi S, Pham V, et al. (2022) The Design, Synthesis, and Evaluation of Novel 9-Arylxanthenedione-Based Allosteric Modulators for the δOpioid Receptor. Journal of Medicinal Chemistry. 65: 12367-12385
Awalt JK, Nguyen ATN, Fyfe TJ, et al. (2022) Examining the Role of the Linker in Bitopic -Substituted Adenosine Derivatives Acting as Biased Adenosine A Receptor Agonists. Journal of Medicinal Chemistry
McDonald JK, van der Westhuizen ET, Pham V, et al. (2022) Biased Profile of Xanomeline at the Recombinant Human M Muscarinic Acetylcholine Receptor. Acs Chemical Neuroscience
Wakeham MCL, Davie BJ, Chalmers DK, et al. (2022) Structural Features of Iperoxo-BQCA Muscarinic Acetylcholine Receptor Hybrid Ligands Determining Subtype Selectivity and Efficacy. Acs Chemical Neuroscience. 13: 97-111
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