Siddhartha S. Mitra, MS PhD

Affiliations: 
2007-2018 Institute for Stem Cell Biology and Regenerative Medicine Stanford University School of Medicine, Palo Alto, CA, United States 
 2018- Pediatrics (Heme/Onc/BMT) University of Colorado School of Medicine, Aurora, CO, United States 
Area:
Neural Stem Cells, Glioma Stem Cells
Website:
https://som.ucdenver.edu/Profiles/Faculty/Profile/27641
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Parents

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Bruce J Nicholson grad student 2005 SUNY Buffalo
 (Understanding the crosstalk between receptor and non-receptor tyrosine kinase signal transduction pathways and Cx43 gap junctional communication.)
Irving L. Weissman research scientist 2010-2018 Stanford University Medical School (FlyTree)
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Publications

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Marquardt V, Theruvath J, Pauck D, et al. (2023) Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation. Journal For Immunotherapy of Cancer. 11
Alimova I, Wang D, Danis E, et al. (2022) Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors. International Journal of Oncology. 60
Lakshmanachetty S, Cruz-Cruz J, Hoffmeyer E, et al. (2021) New Insights into the Multifaceted Role of Myeloid-Derived Suppressor Cells (MDSCs) in High-Grade Gliomas: From Metabolic Reprograming, Immunosuppression, and Therapeutic Resistance to Current Strategies for Targeting MDSCs. Cells. 10
Cole AP, Hoffmeyer E, Chetty SL, et al. (2020) Microglia in the Brain Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1273: 197-208
Theruvath J, Sotillo E, Mount CW, et al. (2020) Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors. Nature Medicine
Gholamin S, Youssef OA, Rafat M, et al. (2019) Irradiation or temozolomide chemotherapy enhances anti-CD47 treatment of glioblastoma. Innate Immunity. 1753425919876690
SoRelle ED, Yecies DW, Liba O, et al. (2019) Spatiotemporal Tracking of Brain-Tumor-Associated Myeloid Cells in Vivo through Optical Coherence Tomography with Plasmonic Labeling and Speckle Modulation. Acs Nano
Mohanty S, Yerneni K, Theruvath JL, et al. (2019) Nanoparticle enhanced MRI can monitor macrophage response to CD47 mAb immunotherapy in osteosarcoma. Cell Death & Disease. 10: 36
Majzner RG, Theruvath JL, Nellan A, et al. (2019) CAR T cells targeting B7-H3, a Pan-Cancer Antigen, Demonstrate Potent Preclinical Activity Against Pediatric Solid Tumors and Brain Tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research
Hutter G, Theruvath J, Graef CM, et al. (2019) Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma. Proceedings of the National Academy of Sciences of the United States of America
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