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Thomas J. Younts, Ph.D.

Affiliations: 
Neuroscience, Physiology and Pharmacology University College London, London, United Kingdom 
Area:
synapse, dendrite, plasticity, integration, signaling, networks, hippocampus, cortex
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"Thomas Younts"
Mean distance: 14.4 (cluster 11)
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Parents

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Pablo Castillo grad student 2007-2014 Yeshiva University
 (Presynaptic forms of long-term plasticity in the mammalian hippocampus.)
Angus Silver post-doc 2015- UCL

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Publications

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Griffiths VA, Valera AM, Lau JY, et al. (2020) Real-time 3D movement correction for two-photon imaging in behaving animals. Nature Methods
Klein ME, Younts TJ, Cobo CF, et al. (2019) Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons. Cell Reports. 29: 1789-1799.e6
Monday HR, Younts TJ, Castillo PE. (2018) Long-Term Plasticity of Neurotransmitter Release: Emerging Mechanisms and Contributions to Brain Function and Disease. Annual Review of Neuroscience
Klein M, Buxbaum A, Younts T, et al. (2017) 788. Local Translation of Synaptic Proteins Supports Plasticity Specifically at Distal Hippocampal Synapses Biological Psychiatry. 81: S320
Jones BW, Deem J, Younts TJ, et al. (2016) Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination. Elife. 5
Younts TJ, Monday HR, Dudok B, et al. (2016) Presynaptic Protein Synthesis Is Required for Long-Term Plasticity of GABA Release. Neuron. 92: 479-492
Younts TJ, Castillo PE. (2014) Endogenous cannabinoid signaling at inhibitory interneurons. Current Opinion in Neurobiology. 26: 42-50
Younts TJ, Chevaleyre V, Castillo PE. (2013) CA1 pyramidal cell theta-burst firing triggers endocannabinoid-mediated long-term depression at both somatic and dendritic inhibitory synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13743-57
Kaeser-Woo YJ, Younts TJ, Yang X, et al. (2013) Synaptotagmin-12 phosphorylation by cAMP-dependent protein kinase is essential for hippocampal mossy fiber LTP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9769-80
Klein ME, Younts TJ, Castillo PE, et al. (2013) RNA-binding protein Sam68 controls synapse number and local β-actin mRNA metabolism in dendrites. Proceedings of the National Academy of Sciences of the United States of America. 110: 3125-30
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