Giulia Tyzack
Affiliations: | University of Cambridge, Cambridge, England, United Kingdom |
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Ziff OJ, Neeves J, Mitchell J, et al. (2023) Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature Communications. 14: 2176 |
Petrić Howe M, Crerar H, Neeves J, et al. (2022) Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis. Genome Research. 32: 1808-1825 |
Taha DM, Clarke BE, Hall CE, et al. (2022) Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis. Brain : a Journal of Neurology |
Ziff OJ, Taha DM, Crerar H, et al. (2021) Reactive astrocytes in ALS display diminished intron retention. Nucleic Acids Research |
Tyzack GE, Manferrari G, Newcombe J, et al. (2020) Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS. Brain : a Journal of Neurology. 143: e66 |
Smethurst P, Risse E, Tyzack GE, et al. (2020) Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 143: 430-440 |
Luisier R, Tyzack GE, Hall CE, et al. (2018) Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nature Communications. 9: 2010 |
Kelley KW, Ben Haim L, Schirmer L, et al. (2018) Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron |
Tyzack GE, Hall CE, Sibley CR, et al. (2017) A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nature Communications. 8: 1164 |
Hall CE, Yao Z, Choi M, et al. (2017) Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Reports. 19: 1739-1749 |