Giulia Tyzack

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
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Ziff OJ, Neeves J, Mitchell J, et al. (2023) Integrated transcriptome landscape of ALS identifies genome instability linked to TDP-43 pathology. Nature Communications. 14: 2176
Petrić Howe M, Crerar H, Neeves J, et al. (2022) Physiological intron retaining transcripts in the cytoplasm abound during human motor neurogenesis. Genome Research. 32: 1808-1825
Taha DM, Clarke BE, Hall CE, et al. (2022) Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis. Brain : a Journal of Neurology
Ziff OJ, Taha DM, Crerar H, et al. (2021) Reactive astrocytes in ALS display diminished intron retention. Nucleic Acids Research
Tyzack GE, Manferrari G, Newcombe J, et al. (2020) Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS. Brain : a Journal of Neurology. 143: e66
Smethurst P, Risse E, Tyzack GE, et al. (2020) Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 143: 430-440
Luisier R, Tyzack GE, Hall CE, et al. (2018) Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nature Communications. 9: 2010
Kelley KW, Ben Haim L, Schirmer L, et al. (2018) Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength. Neuron
Tyzack GE, Hall CE, Sibley CR, et al. (2017) A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nature Communications. 8: 1164
Hall CE, Yao Z, Choi M, et al. (2017) Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS. Cell Reports. 19: 1739-1749
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