William Schmitz, Ph.D.
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organic chemistryGoogle:
"William Schmitz"Mean distance: 8.02 | S | N | B | C | P |
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Publications
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| Hill MD, Fang H, Norris D, et al. (2022) Development of BET Inhibitors as Potential Treatments for Cancer: Optimization of Pharmacokinetic Properties. Acs Medicinal Chemistry Letters. 13: 1165-1171 |
| Li J, Smith D, Krishnananthan S, et al. (2012) An efficient, direct bis-ortho-chlorination of 4-(difluoromethoxy)aniline and its application to the synthesis of BMS-665053, a potent and selective pyrazinone-containing corticotropin-releasing factor-1 receptor antagonist Organic Process Research and Development. 16: 156-159 |
| Schmitz WD, Brenner AB, Bronson JJ, et al. (2010) 5-arylamino-1,2,4-triazin-6(1H)-one CRF1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 3579-83 |
| Hartz RA, Ahuja VT, Schmitz WD, et al. (2010) Synthesis and structure-activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20: 1890-4 |
| SCHMITZ WD, ROMO D. (2010) ChemInform Abstract: A New Route to 2-Substituted δ2-Thiazolines: Stille Cross- Couplings of 2-Bromo-δ2-thiazolines. Cheminform. 27: no-no |
| Hartz RA, Ahuja VT, Arvanitis AG, et al. (2009) Synthesis, structure-activity relationships, and in vivo evaluation of N3-phenylpyrazinones as novel corticotropin-releasing factor-1 (CRF1) receptor antagonists. Journal of Medicinal Chemistry. 52: 4173-91 |
| Hartz RA, Ahuja VT, Rafalski M, et al. (2009) In vitro intrinsic clearance-based optimization of N3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists. Journal of Medicinal Chemistry. 52: 4161-72 |
| Hartz RA, Ahuja VT, Rafalski M, et al. (2009) Corrections to in vitro intrinsic clearance-based optimization of N 3-phenylpyrazinones as corticotropin-releasing factor-1 (CRF 1) receptor antagonists (Journal of Medicinal Chemistry (2009) 52, (4161-4172) DOI: 10.1021/jm900302q] Journal of Medicinal Chemistry. 52: 5770 |
| Schmitz WD, Denhart DJ, Brenner AB, et al. (2005) Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs). Bioorganic & Medicinal Chemistry Letters. 15: 1619-21 |
| Romo D, Rzasa RM, Schmitz WD, et al. (2000) Total synthesis of marine natural products driven by novel structure, potent biological activity, and/or synthetic methodology. Ernst Schering Research Foundation Workshop. 103-48 |