Emmanuel Kostakis
Affiliations: | 2007 | Boston University, Boston, MA, United States |
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"Emmanuel Kostakis"Mean distance: 15.08 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| David H. Farb | grad student | 2007 | Boston University | |
| (Dual regulation of N -methyl -D -aspartate receptor function by neuroactive steroids.) | ||||
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| Kostakis E, Smith C, Jang MK, et al. (2013) The neuroactive steroid pregnenolone sulfate stimulates trafficking of functional N-methyl D-aspartate receptors to the cell surface via a noncanonical, G protein, and Ca2+-dependent mechanism. Molecular Pharmacology. 84: 261-74 |
| Kostakis E, Jang MK, Russek SJ, et al. (2011) A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons. Journal of Neurochemistry. 119: 486-96 |
| Berezhnoy D, Gravielle MC, Downing S, et al. (2008) Pharmacological Properties of DOV 315,090, an ocinaplon metabolite. Bmc Pharmacology. 8: 11 |
| Popik P, Kostakis E, Krawczyk M, et al. (2006) The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors. The Journal of Pharmacology and Experimental Therapeutics. 319: 1244-52 |
| Lippa A, Czobor P, Stark J, et al. (2005) Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator. Proceedings of the National Academy of Sciences of the United States of America. 102: 7380-5 |