William (Bill) R. Brinkley, PhD, Iowa State University

Affiliations: 
Baylor College of Medicine, Houston, TX 
Area:
mitotic apparatus
Website:
http://www.bcm.edu/star/?PMID=3002
Google:
"William (Bill) Brinkley"
Bio:

Postdoctoral, University of Texas M.D. Anderson Cancer Center.
http://www.ascb.org/ascbpost/index.php/ascbpost-home/item/300-giants-of-the-cytoskeleton-win-e-b-wilson-medal

Brinkley notably studied the centromere where he and his coworkers provided some of the early studies of the kinetochore and chromosome attachment to the mitotic spindle.

Mean distance: 16.74 (cluster 28)
 
SNBCP
Cross-listing: BCM Tree

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Publications

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Brinkley WR, Perry G. (2014) Lester (Skip) Binder (1949-2013): in the beginning was tau. Journal of Alzheimer's Disease : Jad. 40: S5
Brinkley WR. (2014) Romancing mitosis and the mitotic apparatus Molecular Biology of the Cell. 25: 3270-3272
Torchia EC, Chen Y, Sheng H, et al. (2009) A genetic variant of Aurora kinase A promotes genomic instability leading to highly malignant skin tumors. Cancer Research. 69: 7207-15
Brinkley WR, Cheeseman IM, Grimes BR, et al. (2009) Preface The Kinetochore: From Molecular Discoveries to Cancer Therapy. v-vii
Lin YG, Immaneni A, Merritt WM, et al. (2008) Targeting aurora kinase with MK-0457 inhibits ovarian cancer growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 5437-46
Okada T, Ohzeki J, Nakano M, et al. (2007) CENP-B controls centromere formation depending on the chromatin context. Cell. 131: 1287-300
Yang F, Camp DG, Gritsenko MA, et al. (2007) Identification of a novel mitotic phosphorylation motif associated with protein localization to the mitotic apparatus. Journal of Cell Science. 120: 4060-70
Landen CN, Lin YG, Immaneni A, et al. (2007) Overexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4098-104
Goepfert TM, Moreno-Smith M, Edwards DG, et al. (2007) Loss of chromosomal integrity drives rat mammary tumorigenesis. International Journal of Cancer. Journal International Du Cancer. 120: 985-94
Goepfert TM, Brinkley WR. (2005) Centrosome Anomalies in Cancer: From Early Observations to Animal Models Centrosomes in Development and Disease. 322-336
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