Hakon Leffler
Affiliations: | 1984-1990 | University of California, San Diego, La Jolla, CA |
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"Hakon Leffler"Mean distance: 9.73 | S | N | B | C | P |
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| Mahanti M, Pal KB, Sundin AP, et al. (2020) Epimers Switch Galectin-9 Domain Selectivity: 3-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal. Acs Medicinal Chemistry Letters. 11: 34-39 |
| Dahlqvist A, Mandal S, Peterson K, et al. (2019) 3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3. Molecules (Basel, Switzerland). 24 |
| Pal KB, Mahanti M, Leffler H, et al. (2019) A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1. International Journal of Molecular Sciences. 20 |
| Dahlqvist A, Zetterberg FR, Leffler H, et al. (2019) Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors. Medchemcomm. 10: 913-925 |
| Kumar R, Ignjatović MM, Peterson K, et al. (2019) Structure and energetics of ligand-fluorine interactions with galectin-3 backbone and side-chain amides - insight into solvation effects and multipolar interactions. Chemmedchem |
| Dahlqvist A, Furevi A, Warlin N, et al. (2019) Stereo- and regioselective hydroboration of 1--methylene pyranoses: discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors. Beilstein Journal of Organic Chemistry. 15: 1046-1060 |
| Stegmayr J, Zetterberg F, Carlsson MC, et al. (2019) Extracellular and intracellular small-molecule galectin-3 inhibitors. Scientific Reports. 9: 2186 |
| Bojić-Trbojević Ž, Jovanović Krivokuća M, Vilotić A, et al. (2019) Human trophoblast requires galectin-3 for cell migration and invasion. Scientific Reports. 9: 2136 |
| Kumar R, Peterson K, Misini Ignjatović M, et al. (2019) Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects. Organic & Biomolecular Chemistry |
| Verteramo ML, Stenström O, Misini Ignjatovic M, et al. (2019) Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding. Journal of the American Chemical Society |