David Bulkley, Ph.D. - Publications

Affiliations: 
2013 Yale University, New Haven, CT 
Area:
Biochemistry, structural chemistry

10 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Lin J, Gagnon MG, Bulkley D, Steitz TA. Conformational changes of elongation factor G on the ribosome during tRNA translocation. Cell. 160: 219-27. PMID 25594181 DOI: 10.1016/J.Cell.2014.11.049  0.569
2014 Polikanov YS, Osterman IA, Szal T, Tashlitsky VN, Serebryakova MV, Kusochek P, Bulkley D, Malanicheva IA, Efimenko TA, Efremenkova OV, Konevega AL, Shaw KJ, Bogdanov AA, Rodnina MV, Dontsova OA, et al. Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Molecular Cell. 56: 531-40. PMID 25306919 DOI: 10.1016/J.Molcel.2014.09.020  0.581
2014 Gagnon MG, Lin J, Bulkley D, Steitz TA. Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome. Science (New York, N.Y.). 345: 684-7. PMID 25104389 DOI: 10.1126/Science.1253525  0.594
2014 Brown JA, Bulkley D, Wang J, Valenstein ML, Yario TA, Steitz TA, Steitz JA. Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix. Nature Structural & Molecular Biology. 21: 633-40. PMID 24952594 DOI: 10.1038/Nsmb.2844  0.534
2014 Bulkley D, Brandi L, Polikanov YS, Fabbretti A, O'Connor M, Gualerzi CO, Steitz TA. The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Reports. 6: 357-65. PMID 24412368 DOI: 10.1016/J.Celrep.2013.12.024  0.577
2012 Xia S, Vashishtha A, Bulkley D, Eom SH, Wang J, Konigsberg WH. Contribution of partial charge interactions and base stacking to the efficiency of primer extension at and beyond abasic sites in DNA. Biochemistry. 51: 4922-31. PMID 22630605 DOI: 10.1021/Bi300296Q  0.517
2012 Gagnon MG, Seetharaman SV, Bulkley D, Steitz TA. Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science (New York, N.Y.). 335: 1370-2. PMID 22422986 DOI: 10.1126/Science.1217443  0.607
2012 Bulkley D, Johnson F, Steitz TA. The antibiotic thermorubin inhibits protein synthesis by binding to inter-subunit bridge B2a of the ribosome. Journal of Molecular Biology. 416: 571-8. PMID 22240456 DOI: 10.1016/J.Jmb.2011.12.055  0.567
2012 Steitz TA, Blaha G, Innis CA, Stanley RE, Bulkley D. Structural studies of the functional complexes of the 50s and 70s ribosome, a major antibiotic target Nato Science For Peace and Security Series a: Chemistry and Biology. 135-148. DOI: 10.1007/978-94-007-2530-0_13  0.606
2010 Bulkley D, Innis CA, Blaha G, Steitz TA. Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proceedings of the National Academy of Sciences of the United States of America. 107: 17158-63. PMID 20876130 DOI: 10.1073/Pnas.1008685107  0.587
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